Evidence map›Paper›PMID 41441106›Full record

ArticleGels (Basel, Switzerland)2025

Graphene Oxide Incorporated Nanohybrid Aerogels as New Generation Drug Carrier Platforms.

Elif Çalışkan Salihi, Shalaleh Hasan Niari Niar, Elif Nur Ulucici, Ebrar Tuğba Gedik, Fatma Betül Zengin, Fulya Samur, Seda Didem Şahin, Turgut Taşkın

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elif Çalışkan SalihiDepartment of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Marmara University, Istanbul 34854, Türkiye.ORCID 0000-0001-7852-3782
Shalaleh Hasan Niari NiarDepartment of Basic Pharmaceutical Sciences, Institute of Health Sciences, Marmara University, Istanbul 34865, Türkiye.
Elif Nur UluciciDepartment of Basic Pharmaceutical Sciences, Institute of Health Sciences, Marmara University, Istanbul 34865, Türkiye.ORCID 0000-0002-8029-594X
Ebrar Tuğba GedikDepartment of Basic Pharmaceutical Sciences, Institute of Health Sciences, Marmara University, Istanbul 34865, Türkiye.
Fatma Betül ZenginDepartment of Pharmacognosy, Faculty of Pharmacy, Marmara University, Istanbul 34854, Türkiye.
Fulya SamurDepartment of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Marmara University, Istanbul 34854, Türkiye.
Seda Didem ŞahinDepartment of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Marmara University, Istanbul 34854, Türkiye.
Turgut TaşkınDepartment of Pharmacognosy, Faculty of Pharmacy, Marmara University, Istanbul 34854, Türkiye.

Funding

Scientific and Technological Research Council of Turkey 1919B012101250
6 · The paper itself

Abstract

By combining the superior capacity of graphene oxide with alginate matrix in a nanohybrid aerogel structure, great potential can be developed for technical features and use in areas such as biomedicine. The aim of this study is the production of graphene oxide incorporated nanohybrid aerogels using ambient pressure drying technique for drug loading and release. The produced nanostructures were identified with electron microscopy, X-ray diffraction, dynamic light scattering, and spectroscopic techniques. The surface area of the nanomaterials was examined by methylene blue method. Drug adsorption capacity of the nanohybrid aerogels was investigated by conducting batch adsorption studies using the model drug diclofenac sodium (DS). The equilibrium time of drug adsorption was determined and adsorption kinetics were modeled. The adsorption equilibrium time of the drug on the adsorbent was found to be 3 h. Equilibrium data were modeled by using the Langmuir and the Freundlich isotherms and according to the Langmuir isotherm, the maximum adsorption capacity was found to be 20.83 mg/g. Results showed the potential of the produced nanohybrid aerogels to be used as drug adsorbents for drug delivery applications. The results obtained from this study will be useful in drug production and treatment.

Indexed as

adsorptionaerogeldiclofenac sodiumgraphene oxidenanohybrid

Identifiers

PMID41441106
PMCPMC12732808

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.