Evidence map›Paper›PMID 41441093›Full record

ArticleGels (Basel, Switzerland)2025

Influence of Retinol Dermal Delivery Formulation on Its Stability Characteristics.

Ioana Lavinia Lixandru Matei, Bogdan Alexandru Sava, Codruta Sarosi, Cristina Maria Dușescu-Vasile, Andreea Iuliana Ionescu, Abeer Baioun, Marian Băjan, Gheorghe Brănoiu, Daniela Roxana Popovici, Andra-Ioana Stănică and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ioana Lavinia Lixandru MateiBotanical SRL, 7 Trandafirilor St., 107059 Tătărani, Romania.ORCID 0000-0002-2634-0615
Bogdan Alexandru SavaDoctoral School of Applied Chemistry and Materials Science, University Politehnica Bucharest-UPB, 313 Splaiul Independenței, 060042 Bucharest, Romania.ORCID 0000-0002-0229-9179
Codruta Sarosi"Raluca Ripan" Institute of Research in Chemistry, Babes-Bolyai University, 1 Mihail Kogălniceanu St., 400084 Cluj-Napoca, Romania.ORCID 0000-0003-2960-9832
Cristina Maria Dușescu-VasilePetroleum Refining Engineering and Environmental Protection Department, Petroleum-Gas University of Ploiesti, 39 Bucharest Boulevard, 100515 Ploiești, Romania.ORCID 0000-0002-2267-9531
Andreea Iuliana IonescuBotanical SRL, 7 Trandafirilor St., 107059 Tătărani, Romania.
Abeer BaiounChemistry Department, Faculty of Science, University of Damascus, Damascus P.O. Box 30621, Syria.ORCID 0009-0008-4765-3937
Marian BăjanPetroleum Refining Engineering and Environmental Protection Department, Petroleum-Gas University of Ploiesti, 39 Bucharest Boulevard, 100515 Ploiești, Romania.ORCID 0000-0002-5856-3944
Gheorghe BrănoiuPetroleum Geology and Reservoir Engineering Department, Petroleum-Gas University of Ploiesti, 39 Bucharest Boulevard, 100515 Ploiești, Romania.ORCID 0000-0002-9562-7564
Daniela Roxana PopoviciChemistry Department, Petroleum-Gas University of Ploiesti, 39 Bucharest Boulevard, 100515 Ploiești, Romania.ORCID 0000-0002-3913-0350
Andra-Ioana StănicăTechnological Highschool "Toma Socolescu", Gheorghe Grigore Cantacuzino St., 328, 100466 Ploiești, Romania.
Dorin BomboșChemistry Department, Petroleum-Gas University of Ploiesti, 39 Bucharest Boulevard, 100515 Ploiești, Romania.ORCID 0009-0001-0515-9032

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New cosmeceuticals formulas (direct emulsion, inverse emulsion and hydrogel), that synergistically combine bioglass with retinol, were prepared and characterized in order to attenuate the irritant potential of retinoids and prolong their therapeutic efficacy. The study evaluates the physicochemical, microbiological and stability characteristics of these formulations. Thus, TGA and DSC analyses revealed stronger interactions between water molecules and those of other organic compounds, with much more being observed in the case of emulsions than in the case of hydrogel, materialized by the delay in water evaporation. The stability of the three types of formulations has been evaluated in two ways: by determining the backscattering variation with the height of the container and analyzing the sample for 6 h and by counting the fraction of small droplets. Both methods demonstrated high stability in the three types of formulations.

Indexed as

bioglassemulsionhydrogelretinolstability

Identifiers

PMID41441093
PMCPMC12733291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.