Evidence map›Paper›PMID 41441024›Full record

ArticleMetabolites2025

Integrative Network Pharmacology and Multi-Omics Analysis Reveal Key Targets and Mechanisms of Saikosaponin B1 Against Acute Lung Injury.

Yuanfei Niu, Meiting Liu, Shuang Cui, Kaiyang Liu, Mengyuan Yang, Xiaozhen Hu, Changhui Zheng, Lianmei Wang, Junling Cao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuanfei NiuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Meiting LiuState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Shuang CuiState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Kaiyang LiuState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Mengyuan YangState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Xiaozhen HuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Changhui ZhengSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Lianmei WangState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Junling CaoSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.

Funding

Caojunling Inheritance Studio for Traditional Chinese Medicine Processing Skills 2025-JNZZS-13Caojunling National Veteran Pharmaceutical Worker Inheritance Studio 2024-255Department of Science and Technology, National 683 Administration of Traditional Chinese Medicine GZY-KJS-2022-057National 684 Administration of Traditional Chinese Medicine Inheritance Base Project [2022]59)Scientific and technological innovation project of China Academy of 688 Chinese Medical Sciences CI2024E003
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acute lung injurymolecular dockingmolecular dynamics simulationmulti-omicsnetwork pharmacologysaikosaponin B1

Identifiers

PMID41441024
PMCPMC12735089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.