Four New Pairs of MetO-Containing Diketopiperazine Enantiomers: Isolation, Synthesis and Potential Anti-Parkinson's Disease Activity.

Yu Lei, Zhenyu Yang, Daichun Li, Xiaojian Liao, Chamari Hettiarachchi, Bingxin Zhao, Shihai Xu

Abstract read

In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yu LeiDepartment of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China.

Zhenyu YangDepartment of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China.

Daichun LiDepartment of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China.

Xiaojian LiaoDepartment of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China.

Chamari HettiarachchiDepartment of Chemistry, University of Colombo, Colombo 00700, Sri Lanka.ORCID 0000-0002-9557-751X

Bingxin ZhaoDepartment of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China.

Shihai XuDepartment of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China.

Funding

Department of Natural Resources of the Guangdong Province [2024]28

6 · The paper itself

Abstract

Four new methionine sulfoxide-containing diketopiperazines, (+)-dysidmetsulfoxide A [(+)-

Indexed as

Antiparkinson AgentsDiketopiperazinesMethionineParkinson DiseasePoriferaAnimalsChinaHumansStereoisomerismZebrafishAntiparkinson AgentsDiketopiperazinesMethioninediketopiperazineDysideamarine spongemethionine sulfoxidesupercritical fluid chromatographytotal synthesis

Identifiers

PMID41440911

DOI10.3390/md23120477

PMCPMC12734934

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.