Evidence map›Paper›PMID 41440903›Full record

ArticleMarine drugs2025

Functionality-Driven Optimization of Green Ultrasound-Assisted Extraction of Antioxidant Compounds from Edible Brown Algae.

Carolina Padrón-Sanz, Samanta García-Oms, Javier Pacheco-Juárez, Lorena Pasquali, Dolores Cejalvo-Lapeña

Abstract read
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carolina Padrón-SanzCentro de Investigación Traslacional San Alberto Magno (CITSAM), Universidad Católica de Valencia, 46001 Valencia, Spain.ORCID 0000-0003-1237-8900
Samanta García-OmsEscuela de Doctorado, Universidad Católica de Valencia, 46001 Valencia, Spain.
Javier Pacheco-JuárezInstituto Universitario de Estudios Ambientales y Recursos Naturales (i-UNAT), Universidad de Las Palmas de Gran Canaria, 35017 Las Palmas, Spain.ORCID 0000-0001-9999-3900
Lorena PasqualiPrimolab S.r.l., 31027 Spresiano, Italy.
Dolores Cejalvo-LapeñaCentro de Investigación Traslacional San Alberto Magno (CITSAM), Universidad Católica de Valencia, 46001 Valencia, Spain.ORCID 0000-0003-4825-1856

Funding

Valencia Catholic University Saint Vincent Martyr [EXP.UCV.2022-159-001]
6 · The paper itself

Abstract

The extraction of antioxidant compounds from brown macroalgae is of growing industrial interest; however, the weak correlation often observed between polyphenol content and antioxidant activity challenges the conventional strategy of optimizing only extraction yield. This study introduces, for the first time in brown macroalgae, a functionality-driven optimization approach in which ultrasound-assisted extraction (UAE) conditions are optimized based on antioxidant activity as the primary response variable, rather than compound concentration. A green UAE process was developed and optimized for four edible brown algae (

Indexed as

AntioxidantsPhaeophyceaeGreen Chemistry TechnologySeaweedSolventsUltrasonicsUltrasonic WavesAntioxidantsSolventsantioxidantsbrown algaeHPLC-FlpigmentspolyphenolsUHPLC-MS/MSultrasound-assisted extraction

Identifiers

PMID41440903
PMCPMC12735051

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.