Evidence map›Paper›PMID 41440886›Full record

ArticleMarine drugs2025

"Hyphae Intertwined, Biomolecules Co-Born"-New Polyketides Induction by Co-Culture of the Mangrove Endophytic Fungus

Ting Feng, Xiaojing Li, Zhenyi Liang, Jing Xu

Abstract read
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ting FengCollaborative Innovation Center of Ecological Civilization, School of Chemistry and Chemical Engineering, Hainan University, Haikou 570228, China.
Xiaojing LiCollaborative Innovation Center of Ecological Civilization, School of Chemistry and Chemical Engineering, Hainan University, Haikou 570228, China.
Zhenyi LiangCollaborative Innovation Center of Ecological Civilization, School of Chemistry and Chemical Engineering, Hainan University, Haikou 570228, China.
Jing XuCollaborative Innovation Center of Ecological Civilization, School of Chemistry and Chemical Engineering, Hainan University, Haikou 570228, China.ORCID 0000-0002-6201-5318

Funding

Collaborative Innovation Center Foundation of Hainan University XTCX2022STB01Guangdong Key Laboratory of Marine Materia Medica Open Fund LMM2021-4Key Research Program of Hainan Province ZDYF2021SHFZ108National Natural Science Foundation of China 82160675/81973229
6 · The paper itself

Abstract

The co-culture technique, mimicking natural microbial interactions, has proven to be successful at activating silent biosynthetic gene clusters (BGCs) to produce novel metabolites or enhance the yield of specific metabolites. To effectively decode induction processes, it is critical to have a comprehensive understanding of intermicrobial interactions across both volatile and non-volatile metabolomes. As part of our attempt to uncover structurally unique and biologically active natural products from mangrove endophytic fungi,

Indexed as

AscomycotaPolyketidesXylarialesAnimalsAntineoplastic AgentsBiological ProductsCell Line, TumorCoculture TechniquesEndophytesGas Chromatography-Mass SpectrometryHumansMiceAntineoplastic AgentsBiological ProductsPolyketideschemical interactionco-culturemangrove endophytic funginon-volatile metabolitesPestalotiopsis sp.Phomopsis asparagivolatile metabolites

Identifiers

PMID41440886
PMCPMC12734679

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.