Evidence map›Paper›PMID 41440884›Full record

ArticleMarine drugs2025

Novel PPAR-γ Agonist from the Soft Coral

Jian-Ang Zeng, Min Sun, Yi Qi, Song-Wei Li, Li-Ting Zhang, Si-Min Pan, Yue-Wei Guo, Ming-Zhi Su, Hui Luo

Abstract read
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jian-Ang ZengGuangdong Engineering Technology Research Center for the Development and Utilization of Mangrove Wetland Medicinal Resources, The Key Lab of Zhanjiang for R&D Marine Microbial Resources in the Beibu Gulf Rim, School of Ocean and Tropical Medicine, Guangdong Medical University, Zhanjiang 524023, China.
Min SunShandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai 264117, China.
Yi QiGuangdong Engineering Technology Research Center for the Development and Utilization of Mangrove Wetland Medicinal Resources, The Key Lab of Zhanjiang for R&D Marine Microbial Resources in the Beibu Gulf Rim, School of Ocean and Tropical Medicine, Guangdong Medical University, Zhanjiang 524023, China.
Song-Wei LiSchool of Medicine, Shanghai University, Shanghai 200444, China.ORCID 0009-0007-9828-7431
Li-Ting ZhangShandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai 264117, China.
Si-Min PanShandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai 264117, China.
Yue-Wei GuoShandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai 264117, China.ORCID 0000-0003-0413-2070
Ming-Zhi SuShandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai 264117, China.
Hui LuoGuangdong Engineering Technology Research Center for the Development and Utilization of Mangrove Wetland Medicinal Resources, The Key Lab of Zhanjiang for R&D Marine Microbial Resources in the Beibu Gulf Rim, School of Ocean and Tropical Medicine, Guangdong Medical University, Zhanjiang 524023, China.ORCID 0000-0001-6121-1715

Funding

Key R&D Program of Shandong Province, China 2024CXPT029 and 2025CXPT012National Natural Science Foundation of China 82404502 and 82304375Shandong Laboratory Program SYS202205
6 · The paper itself

Abstract

Two previously undescribed highly oxygenated cembrane-type diterpenes, namely sarcocraol A (

Indexed as

AnthozoaDiterpenesGlucosePPAR gamma3T3-L1 CellsAnimalsChinaHep G2 CellsHumansHypoglycemic AgentsMicePPAR-gamma AgonistsDiterpenesGlucoseHypoglycemic AgentsPPAR gammaPPAR-gamma Agonistscembrane-type diterpenesglucose uptakelipid metabolismPPAR-γ agonistSarcophyton crassocaulesoft coralX-ray diffraction

Identifiers

PMID41440884
PMCPMC12734517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.