Evidence map›Paper›PMID 41440882›Full record

ArticleMarine drugs2025

6-Isoprenylindole-3-carboxylic Acid with an Anti-Melanogenic Activity from a Marine-Derived

Minjeong Kim, Eun-Young Lee, Ga-Eun Shin, Jungwook Chin, Hongchan An, Sang-Jip Nam, Kyung-Min Lim

Abstract read
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Minjeong KimCollege of Pharmacy, Ewha Womans University, Seoul 03760, Republic of Korea.
Eun-Young LeeCollege of Pharmacy, Ewha Womans University, Seoul 03760, Republic of Korea.
Ga-Eun ShinCollege of Pharmacy, Ewha Womans University, Seoul 03760, Republic of Korea.
Jungwook ChinCureverse, Inc., H2 Building, KIST, Seoul 02792, Republic of Korea.ORCID 0000-0001-6060-0508
Hongchan AnNew Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, Republic of Korea.ORCID 0000-0001-6689-9571
Sang-Jip NamDepartment of Chemistry and Nanoscience, Ewha Womans University, Seoul 03760, Republic of Korea.ORCID 0000-0002-0944-6565
Kyung-Min LimCollege of Pharmacy, Ewha Womans University, Seoul 03760, Republic of Korea.ORCID 0000-0002-1517-7680

Funding

Ministry of Health and Welfare Korea RS-2024-00344565National Research Foundation of Korea NRF- RS-2023-00247577, and 2022R1A2C1011848
6 · The paper itself

Abstract

In this study, we report the isolation of the known compound 6-isoprenylindole-3-carboxylic acid (SJ196), a prenylated indole derivative, from a marine

Indexed as

IndolesMelaninsStreptomycesAnimalsAntioxidantsAquatic OrganismsCell Line, TumorHumansMelanoma, ExperimentalMiceMicrophthalmia-Associated Transcription FactorReactive Oxygen SpeciesSignal TransductionSkinSkin PigmentationAntioxidantsIndolesMelaninsMicrophthalmia-Associated Transcription FactorReactive Oxygen Species3D modelsanti-melanogenic activityantioxidant activitymarine-derived actinomycetesmelanocyteskin-brighteningStreptomyces sp.

Identifiers

PMID41440882
PMCPMC12734698

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.