Evidence map›Paper›PMID 41440880›Full record

ArticleJournal of cardiovascular development and disease2025

Advancing Minimally Invasive Mitral Valve Surgery: Early Outcomes of a Total Endoscopic 2D and 3D Approach.

Carlo Savini, Mariafrancesca Fiorentino, Diego Sangiorgi, Simone Calvi, Antonino Costantino, Elena Tenti, Elisa Mikus

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carlo SaviniCardiovascular Department, Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola, Italy.ORCID 0000-0003-4197-7486
Mariafrancesca FiorentinoCardiovascular Department, Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola, Italy.ORCID 0000-0002-1396-4330
Diego SangiorgiCardiovascular Department, Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola, Italy.ORCID 0009-0003-6666-3480
Simone CalviCardiovascular Department, Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola, Italy.
Antonino CostantinoCardiovascular Department, Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola, Italy.ORCID 0000-0002-3449-6986
Elena TentiCardiovascular Department, Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola, Italy.ORCID 0000-0001-6974-0849
Elisa MikusCardiovascular Department, Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola, Italy.ORCID 0000-0003-2892-8700

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe minimally invasive approach is increasingly recognized as the standard for surgical management of mitral valve disease. Advances in endoscopic visualization and surgical instrumentation have enhanced precision while minimizing trauma, improving both functional and esthetic outcomes. This study presents a single-center experience with total endoscopic mitral valve repair (MVR) performed using two- or three-dimensional video-assisted technology.

methodsBetween October 2022 and September 2025, 239 patients underwent total endoscopic MVR at our institution. Demographic, operative, and postoperative data were collected and analyzed.

resultsMedian age was 63 years, with 64.4% male. Median logistic EuroSCORE and EuroSCORE II were 2.53 and 0.83, respectively. Most patients were NYHA class II (54.4%), and 47.7% had pulmonary hypertension. Mitral annuloplasty was performed in 99.2% of cases; 78.6% received Gore-Tex chordae, 6.3% underwent posterior leaflet resection, and 11.7% edge-to-edge repair. Conversion to sternotomy occurred in 0.4%. In-hospital mortality was 1.3%; stroke occurred in 0.4%. Postoperative atrial fibrillation developed in 26.8%, while major complications such as sepsis (2.1%) and renal failure requiring dialysis (1.3%) were infrequent. Median ventilation time was 5 h, ICU stay was 2 days, and hospital stay was 7 days. Pre-discharge echocardiography showed ≤mild regurgitation in 99.2%.

conclusionsTotal endoscopic MVR using two- or three-dimensional video assistance is safe, feasible, and yields excellent clinical, functional, and cosmetic results, with low morbidity and rapid recovery.

Indexed as

minimally invasive cardiac surgerymitral valve repairtotal endoscopic cardiac surgery

Identifiers

PMID41440880
PMCPMC12734116

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.