Evidence map›Paper›PMID 41440858›Full record

ReviewJournal of cardiovascular development and disease2025

Atrioventricular Junction Ablation with High-Definition Recording of Atrioventricular Node Potential.

Andrea Matteucci, Enrico Maggio, Domenico Dardani, Maurizio Russo, Marco Galeazzi, Federico Nardi, Silvio Fedele, Claudio Pandozi, Furio Colivicchi

Abstract readReview
In one paragraph

Review in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrea MatteucciClinical and Rehabilitation Cardiology Division, San Filippo Neri Hospital, 00135 Rome, Italy.ORCID 0000-0002-8831-6178
Enrico MaggioDepartment of Cardiovascular, Respiratory, Nephrological, Anesthesiological and Geriatric Sciences, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0002-9758-8482
Domenico DardaniDepartment of Clinical and Molecular Medicine, Sapienza University of Rome, 00189 Rome, Italy.
Maurizio RussoClinical and Rehabilitation Cardiology Division, San Filippo Neri Hospital, 00135 Rome, Italy.
Marco GaleazziClinical and Rehabilitation Cardiology Division, San Filippo Neri Hospital, 00135 Rome, Italy.ORCID 0000-0002-6184-5547
Federico NardiCardiology Unit, Santo Spirito Hospital, Casale Monferrato, 15033 Alessandria, Italy.
Silvio FedeleDepartment of Interventional Cardiology, UOC Cardiologia, Sandro Pertini Hospital, 00157 Rome, Italy.ORCID 0009-0001-8518-0877
Claudio PandoziClinical and Rehabilitation Cardiology Division, San Filippo Neri Hospital, 00135 Rome, Italy.
Furio ColivicchiClinical and Rehabilitation Cardiology Division, San Filippo Neri Hospital, 00135 Rome, Italy.ORCID 0000-0001-7187-2234

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrioventricular (AV) node ablation represents an established therapeutic option in the management of atrial fibrillation (AF) and other atrial tachyarrhythmias, particularly in patients with symptomatic tachycardia who remain unresponsive or intolerant to pharmacological therapy. The procedure is often considered in cases of refractory arrhythmias, antiarrhythmic drugs intolerance, or tachycardiomyopathy, and plays a key role in optimizing outcomes in patients undergoing cardiac resynchronization therapy, where achieving adequate biventricular pacing is otherwise compromised by rapid ventricular responses. Traditionally, AV node ablation is performed using radiofrequency energy delivered at the region of the His bundle, guided by the earliest His potential recordings. However, the anatomical complexity of the AV node and Koch's triangle poses important challenges, including the risk of incomplete ablation, persistence of conduction, lack of reliable junctional escape rhythms, and increased risk of proarrhythmia. Recent advances in high-resolution mapping and electroanatomical guidance have enabled a more precise anatomical approach, selectively targeting the compact AV node while reducing collateral injury. These developments offer the potential for improved procedural safety, long-term efficacy, and a more standardized strategy for patient management. This review summarizes current evidence, techniques, and clinical implications of AV node ablation, highlighting its role in the evolving landscape of arrhythmia treatment.

Indexed as

atrial fibrillationatrioventricular node ablationatrioventricular node potentialelectroanatomical mappingtachycardiomyopathy

Identifiers

PMID41440858
PMCPMC12733511

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.