Evidence map›Paper›PMID 41440617›Full record

ArticleJournal of functional biomaterials2025

Properties of 3-Dimensional Cell Cultivation Matrices and Scaffolds in Magnetic Resonance Imaging at 3 Tesla.

Rebecca Wißmann, Petros Martirosian, Marina Danalache, Stefanie Elser, Jürgen Machann, Fritz Schick

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rebecca WißmannDepartment of Diagnostic and Interventional Radiology, University Hospital of Tübingen, D-72076 Tübingen, Germany.ORCID 0000-0002-3814-8970
Petros MartirosianDepartment of Diagnostic and Interventional Radiology, University Hospital of Tübingen, D-72076 Tübingen, Germany.
Marina DanalacheDepartment of Orthopedic Surgery, University Hospital of Tübingen, D-72076 Tübingen, Germany.
Stefanie ElserDepartment of Diagnostic and Interventional Radiology, University Hospital of Tübingen, D-72076 Tübingen, Germany.
Jürgen MachannDepartment of Diagnostic and Interventional Radiology, University Hospital of Tübingen, D-72076 Tübingen, Germany.ORCID 0000-0002-4458-5886
Fritz SchickDepartment of Diagnostic and Interventional Radiology, University Hospital of Tübingen, D-72076 Tübingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural or synthetic scaffolds are essential for developing three-dimensional (3D) cell culture models, as they provide structural stability and accurately replicate the cellular microenvironment. When integrated into optimized setups, scaffold-supported cellular aggregates, such as spheroids, can be non-destructively characterized and monitored using 3T Magnetic Resonance Imaging (MRI). However, a significant technical limitation is the presence of MR artifacts generated by scaffolds, which can severely obscure the visualization of the embedded spheroids. This study systematically evaluated the suitability of various scaffolds and matrices (including Matrigel

Indexed as

3D culturemagnetic resonance imaging (MRI)matricesproton magnetic resonance spectroscopy (1H-MRS)regenerative medicinescaffoldsspheroidstissue engineeringtumor model

Identifiers

PMID41440617
PMCPMC12733782

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.