ArticleMedical sciences (Basel, Switzerland)2025
Biochemical and Hematological Predictors of Mortality in Thai Patients with COVID-19.
Article in Medical sciences (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- ICU Admission and Post-Discharge Mortality in COVID-19: Different Risk Factors Across Clinical Phases.Medical sciences (Basel, Switzerland) · 2026Observational
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10 authors.
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Abstract
backgroundCoronavirus disease (COVID-19), caused by SARS-CoV-2 infection, presents a broad spectrum of clinical manifestations, ranging from asymptomatic cases to severe and fatal outcomes. Studies have shown that laboratory parameters fluctuate in patients with COVID-19, and these parameters serve as valuable biomarkers for monitoring disease progression. This study examines the relationship between changes in biochemical and hematological markers and patient survival among early COVID-19 cases. MATERIALS AND
methodsIn this retrospective cohort study, data from adult (≥18 years) hospitalized COVID-19 patients with positive PCR results at HRH Princess Maha Chakri Sirindhorn Medical Center, Srinakharinwirot University, Nakhon Nayok, Thailand, between March and December 2021, were analyzed. Univariate and multivariate logistic regression analyses were conducted on mortality-related laboratory parameters. All measures are reported as adjusted odds ratios (aORs) with 95% confidence intervals (CIs).
resultsThe cohort included 397 patients with pneumonia (median age: 52.2 years (IQR: 40.5-64.6); 61.96% female). Among them, 42 patients (10.58%) succumbed during hospitalization, with a median hospital stay of 12.92 days (IQR: 10.03-15.94). Independent mortality predictors were identified as follows: age (aOR = 1.11; 95% CI: 1.04-1.19;
conclusionsOur findings suggest that age, potassium, creatinine, hemoglobin A1c, red cell distribution width, and platelet count are significant predictors of mortality risk in patients with COVID-19. Clinicians should consider these biochemical and hematological markers critically before initiating treatment for COVID-19 patients.
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