Evidence map›Paper›PMID 41440318›Full record

ArticleDentistry journal2025

A Rare Case of Mandibular Chondrosarcoma Arising from Fibrous Dysplasia.

Ciprian Roi, Ruxandra Elena Luca, Alexandra Roi, Adrian Nicoară, Sorina Fanan, Flavia Zară, Raluca Maria Cloșca, Mircea Riviș

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Dentistry journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ciprian RoiDepartment of Anesthesiology and Oral Surgery, Research Center of Dento-Alveolar Surgery, Anesthesia and Sedation in Dental Medicine, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.ORCID 0000-0002-3214-9278
Ruxandra Elena LucaUniversity Clinic of Oral Rehabilitation and Dental Emergencies, Faculty of Dentistry, Interdisciplinary Research Center for Dental Medical Research, Lasers and Innovative Technologies, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania.ORCID 0000-0001-7323-2687
Alexandra RoiDepartment of Oral Pathology, Multidisciplinary Center for Research, Evaluation, Diagnosis and Therapies in Oral Medicine, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.ORCID 0000-0003-4790-4560
Adrian NicoarăDepartment of Anesthesiology and Oral Surgery, Research Center of Dento-Alveolar Surgery, Anesthesia and Sedation in Dental Medicine, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.
Sorina FananClinical County Emergency Hospital Timisoara, Oral and Maxillofacial Surgery Deprtment, 5 Take Ionescu Street, 300062 Timisoara, Romania.
Flavia ZarăDepartment of Pathology, Emergency City Hospital and Department of Microscopic Morphology, Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.ORCID 0000-0002-5755-179X
Raluca Maria CloșcaDepartment of Pathology, Emergency City Hospital and Department of Microscopic Morphology, Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.ORCID 0009-0001-1397-1864
Mircea RivișDepartment of Anesthesiology and Oral Surgery, Research Center of Dento-Alveolar Surgery, Anesthesia and Sedation in Dental Medicine, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.ORCID 0000-0001-5626-1064

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibrous dysplasia is an uncommon, intramedullary fibro-osseous lesion representing approximately 5% to 7% of benign fibro-osseous lesions. The incidence of malignant transformation of fibrous dysplasia is considered very rare. The aim of this case report is to present a rare case of a chondro-sarcomatous transformation of a case previously diagnosed with mandibular fibrous dysplasia, a patient who was initially referred for a gingival tumoral extirpation in the third quadrant. A 57-year-old female patient presented for a consultation and, after a biopsy, was diagnosed with fibrous dysplasia of the mandibular bone. After two interventions of surgical removal of the lesion, the malignant transformation of chondrosarcoma occurred, which was identified by radiologic and histopathologic investigations, with the overall AJCC staging being pT1N0M0, G3. Radical resection of the mandibular bone with free margins of tumor was performed. Malignant transformation of mandibular fibrous dysplasia is a very rare and challenging complication of this disease. Early recognition and proper surgical treatment must be the key actions from doctors and clinicians.

Indexed as

chondrosarcomafibrous dysplasiamalignant transformation

Identifiers

PMID41440318
PMCPMC12732114

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