Evidence map›Paper›PMID 41440265›Full record

ArticleBiosensors2025

Ultrasensitive and Label-Free Detection of Phosphorylated Tau-217 Protein in Alzheimer's Disease Using Carbon Nanotube Field-Effect Transistor (CNT-FET) Biosensor.

Jiao Wang, Keyu Yao, Jiahua Li, Duo Wai-Chi Wong, James Chung-Wai Cheung

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiao WangDepartment of Biomedical Engineering, Faculty of Engineering, The Hong Kong Polytechnic University, Hong Kong 999077, China.ORCID 0009-0008-1025-6452
Keyu YaoDepartment of Biomedical Engineering, Faculty of Engineering, The Hong Kong Polytechnic University, Hong Kong 999077, China.ORCID 0009-0003-0404-6794
Jiahua LiShenzhen Research Institute, The Hong Kong Polytechnic University, Shenzhen 518057, China.ORCID 0000-0001-7597-8829
Duo Wai-Chi WongDepartment of Biomedical Engineering, Faculty of Engineering, The Hong Kong Polytechnic University, Hong Kong 999077, China.ORCID 0000-0002-8805-1157
James Chung-Wai CheungDepartment of Biomedical Engineering, Faculty of Engineering, The Hong Kong Polytechnic University, Hong Kong 999077, China.ORCID 0000-0001-7446-0569

Funding

Innovation and Technology Commission PRP/003/24FX
6 · The paper itself

Abstract

Early diagnosis of Alzheimer's disease (AD) remains challenging due to the extremely low concentration of relevant biomarkers and the limited sensitivity of conventional detection techniques. In this study, we present a carbon nanotube field-effect transistor (CNT-FET) immunosensor for label-free detection of phosphorylated tau at threonine 217 (p-tau217). The device employs a Y

Indexed as

Alzheimer DiseaseBiosensing TechniquesNanotubes, Carbontau ProteinsGoldHumansImmunoassayLimit of DetectionMetal NanoparticlesPhosphorylationTransistors, ElectronicGoldNanotubes, Carbontau ProteinsAlzheimer’s diseasebiosensorCNT-FETp-tau217

Identifiers

PMID41440265
PMCPMC12730868

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.