Evidence map›Paper›PMID 41440247›Full record

ReviewBiosensors2025

Nanomaterials-Enhanced Electrochemical Biosensors for Epithelial Cancer Diagnosis: Recent Advances.

Matías Regiart, Alba M Gimenez, Francisco G Ortega, Germán E Gómez, Juan Sainz, Gonzalo R Tortella, Martín A Fernández-Baldo

Abstract readReview
In one paragraph

Review in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matías RegiartInstituto de Química de San Luis, Facultad de Química, Universidad Nacional de San Luis, INQUISAL (UNSL-CONICET), Ejército de los Andes 950, San Luis D5700BWS, Argentina.ORCID 0000-0001-9255-6222
Alba M GimenezDepartment of Immunology, Institute of Biomedical Sciences, Universidade de São Paulo (USP), São Paulo 05508-220, Brazil.
Francisco G OrtegaGENYO, Centre for Genomics and Oncological Research, Pfizer/University of Granada/Andalusian Regional Government PTS, Granada, Avenida de la Ilustración, 114, 18016 Granada, Spain.
Germán E GómezInstituto de Investigaciones en Tecnología Química (INTEQUI), Departamento de Química, Universidad Nacional de San Luis (UNSL), CONICET, Ejército de los Andes 950, San Luis D5700BWS, Argentina.ORCID 0000-0003-4963-5202
Juan SainzGenomic Oncology Area, GENYO, Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS, 18016 Granada, Spain.ORCID 0000-0002-9355-2423
Gonzalo R TortellaCentro de Excelencia en Investigación Biotecnológica Aplicada al Medio Ambiente (CIBAMA), Facultad de Ingeniería y Ciencias, Universidad de La Frontera, Av. Francisco Salazar 01145, Temuco 4811230, Chile.ORCID 0000-0001-7069-7454
Martín A Fernández-BaldoInstituto de Química de San Luis, Facultad de Química, Universidad Nacional de San Luis, INQUISAL (UNSL-CONICET), Ejército de los Andes 950, San Luis D5700BWS, Argentina.ORCID 0000-0003-0385-2391

Funding

Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación PICT-2021-GRF-TI-00136Consejo Nacional de Investigaciones Científicas y Técnicas PIP-11220200100033COInstituto de Salud Carlos III PI22_01275, CP23/00134, DTS23_00030National University of San Luis PROICO 1026 02-2220Universidad de Granada P32/22/02
6 · The paper itself

Abstract

In recent years, the interest in electrochemical biosensors has been constantly growing for epithelial cancer diagnosis and prognosis. The incorporation of the different nanomaterials as metal nanoparticles, magnetic nanoparticles, carbon nanomaterials, Metal-Organic Frameworks (MOFs), and nanocomposites, along with specific monoclonal antibodies, and nucleic acids (aptamers) has improved both sensitivity and specificity in these methodologies. In this review, we have presented examples of electrochemical biosensors for the determination of different epithelial cancer biomarkers. Based on numerous reports in the recent literature, we highlight the use of single and multiplexed analytical platforms for the quantification of epithelial cancer biomarkers. In addition, we outline potential development pathways, current challenges, and future prospects in the field of electrochemical immuno-, apta-, and genosensors.

Indexed as

Biosensing TechniquesElectrochemical TechniquesNanostructuresNeoplasms, Glandular and EpithelialBiomarkers, TumorHumansBiomarkers, Tumorbiosensorcancer diagnosiselectrochemicalnanomaterialreal samplestumor biomarker

Identifiers

PMID41440247
PMCPMC12730643

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.