Evidence map›Paper›PMID 41440226›Full record

ReviewCurrent oncology (Toronto, Ont.)2025

Precision Care for Hereditary Urologic Cancers: Genetic Testing, Counseling, Surveillance, and Therapeutic Implications.

Takatoshi Somoto, Takanobu Utsumi, Rino Ikeda, Naoki Ishitsuka, Takahide Noro, Yuta Suzuki, Shota Iijima, Yuka Sugizaki, Ryo Oka, Takumi Endo and 2 more

Abstract readReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Takatoshi SomotoDepartment of Urology, Toho University Sakura Medical Center, Sakura 285-8741, Japan.
Takanobu UtsumiDepartment of Urology, Toho University Sakura Medical Center, Sakura 285-8741, Japan.ORCID 0000-0002-9423-7361
Rino IkedaDepartment of Urology, Toho University Sakura Medical Center, Sakura 285-8741, Japan.
Naoki IshitsukaDepartment of Urology, Toho University Sakura Medical Center, Sakura 285-8741, Japan.
Takahide NoroDepartment of Urology, Toho University Sakura Medical Center, Sakura 285-8741, Japan.
Yuta SuzukiDepartment of Urology, Toho University Sakura Medical Center, Sakura 285-8741, Japan.
Shota IijimaDepartment of Urology, Toho University Sakura Medical Center, Sakura 285-8741, Japan.
Yuka SugizakiDepartment of Urology, Toho University Sakura Medical Center, Sakura 285-8741, Japan.
Ryo OkaDepartment of Urology, Toho University Sakura Medical Center, Sakura 285-8741, Japan.
Takumi EndoDepartment of Urology, Toho University Sakura Medical Center, Sakura 285-8741, Japan.
Naoto KamiyaDepartment of Urology, Toho University Sakura Medical Center, Sakura 285-8741, Japan.ORCID 0000-0002-4183-2490
Hiroyoshi SuzukiDepartment of Urology, Toho University Sakura Medical Center, Sakura 285-8741, Japan.ORCID 0000-0001-5838-114X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hereditary predisposition substantially shapes prevention and management across urologic oncology. This narrative review synthesizes contemporary, practice-oriented guidance on whom to test, what to test, how to act on results, and how to implement care equitably for hereditary forms of prostate cancer, renal cell carcinoma (RCC), urothelial carcinoma, pheochromocytoma/paraganglioma (PPGL), and adrenocortical carcinoma (ACC). We delineate between forms of indication-driven germline testing (e.g., universal testing in metastatic prostate cancer; early-onset, bilateral/multifocal, or syndromic RCC; reflex tumor mismatch repair (MMR)/microsatellite instability (MSI) screening in upper-tract urothelial carcinoma (UTUC); universal testing in PPGL; universal

Indexed as

Genetic CounselingGenetic TestingPrecision MedicineUrologic NeoplasmsGenetic Predisposition to DiseaseHumansMaleadrenocortical carcinomagenetic counselinghereditary cancer syndromesLynch syndromepheochromocytoma and paragangliomaprostate cancerrenal cell carcinomaupper tract urothelial carcinoma

Identifiers

PMID41440226
PMCPMC12731482

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.