Evidence map›Paper›PMID 41440185›Full record

ArticleCurrent oncology (Toronto, Ont.)2025

Pancreatico-Jejunostomy Fistula After Pancreaticoduodenectomy: Where Do We Stand? Results from an International Survey.

Silvio Caringi, Michele Tedeschi, Antonella Delvecchio, Annachiara Casella, Valentina Ferraro, Cataldo De Palma, Rosalinda Filippo, Matteo Stasi, Tommaso Maria Manzia, Riccardo Memeo and 1 more

Abstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Silvio CaringiUnit of Hepato-Biliary and Pancreatic Surgery, "F. Miulli" General Hospital, Acquaviva delle Fonti, 70021 Bari, Italy.ORCID 0009-0008-6007-8834
Michele TedeschiUnit of Hepato-Biliary and Pancreatic Surgery, "F. Miulli" General Hospital, Acquaviva delle Fonti, 70021 Bari, Italy.ORCID 0000-0002-2101-5418
Antonella DelvecchioUnit of Hepato-Biliary and Pancreatic Surgery, "F. Miulli" General Hospital, Acquaviva delle Fonti, 70021 Bari, Italy.ORCID 0000-0002-7759-4340
Annachiara CasellaUnit of Hepato-Biliary and Pancreatic Surgery, "F. Miulli" General Hospital, Acquaviva delle Fonti, 70021 Bari, Italy.
Valentina FerraroUnit of Hepato-Biliary and Pancreatic Surgery, "F. Miulli" General Hospital, Acquaviva delle Fonti, 70021 Bari, Italy.
Cataldo De PalmaIRCCS Humanitas Research Hospital, Pancreatic Surgery, Via Alessandro Manzoni 56, 20089 Rozzano, Italy.ORCID 0009-0001-0997-9425
Rosalinda FilippoUnit of Hepato-Biliary and Pancreatic Surgery, "F. Miulli" General Hospital, Acquaviva delle Fonti, 70021 Bari, Italy.
Matteo StasiUnit of Hepato-Biliary and Pancreatic Surgery, "F. Miulli" General Hospital, Acquaviva delle Fonti, 70021 Bari, Italy.
Tommaso Maria ManziaTransplant and HPB Unit, Department of Surgery Sciences, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-4636-3478
Riccardo MemeoUnit of Hepato-Biliary and Pancreatic Surgery, "F. Miulli" General Hospital, Acquaviva delle Fonti, 70021 Bari, Italy.ORCID 0000-0002-1668-932X
Pancreatico-Jejunostomy Fistula Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPancreatico-duodenectomy (PD) remains one of the most complex abdominal surgeries, and pancreatico-jejunostomy (PJ) fistula is its most critical postoperative complication. In efforts to reduce the incidence of postoperative pancreatic fistula (POPF), several PJ techniques and adjuncts, including stents, have been recommended. This article presents data from an international survey regarding PJ methods, the use of pancreatic stents, and their correlation with POPF rates from surgical centers worldwide.

methodsA nine-item online questionnaire was sent globally through social networks, individual mailing lists, and the ASHBPS mailing list. Data were analyzed through the Student's

resultsA total of 122 units of pancreatic surgery from 26 countries distributed across five continents responded to the survey. Most centers performed less than 50 PDs a year, preferred a duct-to-mucosa PJ, and employed a stent routinely. Mean POPF grade B and C incidences were lower in high-volume (15.24% ± 7.29 and 3.95% ± 2.39) and in PJ stent-using centers (16.25% ± 8.7 and 5.37% ± 7.49).

conclusionsInstitutional case volume and stent usage are more crucial determinants of POPF incidence than the PJ technique itself. Centralization and standardization of PD procedures are related to reductions in major fistula rates.

Indexed as

Pancreatic FistulaPancreaticoduodenectomyPancreaticojejunostomyPostoperative ComplicationsHumansSurveys and Questionnairespancreatic anastomosespancreatic fistulapancreatic stentpancreatic surgery

Identifiers

PMID41440185
PMCPMC12731699

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.