Evidence map›Paper›PMID 41440179›Full record

Trial reportCurrent oncology (Toronto, Ont.)2025

Effects of Resistance Exercise on Quality of Life, Anxiety, Depression, Sleep Quality and Inflammatory Parameters in Patients with Colorectal Cancer Undergoing Active Treatment: A Pilot Randomized Clinical Trial.

Juan Luis Sánchez-González, Jesus Perez, Eduardo José Fernández-Rodríguez, Emilio Fonseca-Sánchez, Yolanda López-Mateos, Claudia María Sanz-Blanco, Francisco Javier Martín-Vallejo, Alberto García-Martín, Carlos Martín-Sánchez

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Current oncology (Toronto, Ont.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Juan Luis Sánchez-GonzálezDepartment of Medicine, Faculty of Medicine, University of Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-4791-6513
Jesus PerezDepartment of Medicine, Faculty of Medicine, University of Salamanca, 37007 Salamanca, Spain.
Eduardo José Fernández-RodríguezInstitute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.ORCID 0000-0002-2175-8545
Emilio Fonseca-SánchezInstitute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.
Yolanda López-MateosInstitute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.
Claudia María Sanz-BlancoInstitute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.
Francisco Javier Martín-VallejoInstitute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.ORCID 0000-0003-3962-7356
Alberto García-MartínInstitute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.ORCID 0000-0002-5427-9743
Carlos Martín-SánchezInstitute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.ORCID 0000-0002-8627-3645

Funding

Colegio Profesional de Fisioterapeutas de Castilla y León, Spain (CPFCYL) S/2024/01503 CO
6 · The paper itself

Abstract

objectiveThe primary objective of this pilot randomized clinical trial was to determine the effect of adding a supervised resistance exercise programme to a home-based physical activity plan on health-related quality of life in patients with colorectal cancer undergoing active treatment. The secondary objectives were to evaluate its effects on anxiety, depression, sleep quality, and inflammatory parameters.

methodsThis is a pilot randomized clinical trial with parallel groups. Patients with CRC were recruited through the Oncology Department at the Salamanca University Health Care Complex in Spain. They were randomly allocated to receive either a home-based physical activity plus a supervised resistance training programme, or the home-based physical activity plan only. The primary outcome was health-related quality of life measures and the secondary outcomes included anxiety, depression and sleep quality evaluations. The supervised training lasted 8 weeks for each patient.

resultsA total of 40 patients were recruited, 20 for each group. Adding a supervised resistance exercise programme to the home-based activity plan improved symptoms related to quality of life, such as fatigue (

conclusionsFatigue and constipation in patients with CRC receiving chemo- and/or immunotherapy may benefit from the introduction of supervised resistance exercise training programmes.

Indexed as

AnxietyColorectal NeoplasmsDepressionQuality of LifeResistance TrainingSleep QualityAgedFemaleHumansInflammationMaleMiddle AgedPilot Projectscolorectal cancerdrug therapymental healthquality of liferesistance training

Identifiers

PMID41440179
PMCPMC12731986

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.