Evidence map›Paper›PMID 41440172›Full record

ReviewBiotech (Basel (Switzerland))2025

Somatic Embryogenesis: A Biotechnological Route in the Production of Recombinant Proteins.

Marco A Ramírez-Mosqueda, Jorge David Cadena-Zamudio, Carlos A Cruz-Cruz, José Luis Aguirre-Noyola, Raúl Barbón, Rafael Gómez-Kosky, Carlos Angulo

Abstract readReview
In one paragraph

Review in Biotech (Basel (Switzerland)), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marco A Ramírez-MosquedaCentro Nacional de Recursos Genéticos-INIFAP, Boulevard de la Biodiversidad No. 400, Rancho las Cruces, Tepatitlán de Morelos 47600, Jalisco, Mexico.ORCID 0000-0002-2477-4612
Jorge David Cadena-ZamudioCentro Nacional de Recursos Genéticos-INIFAP, Boulevard de la Biodiversidad No. 400, Rancho las Cruces, Tepatitlán de Morelos 47600, Jalisco, Mexico.ORCID 0000-0002-2855-4561
Carlos A Cruz-CruzFacultad de Ciencias Químicas, Universidad Veracruzana, Prolongación Oriente 6, No. 1009, Orizaba 94340, Veracruz, Mexico.ORCID 0000-0002-5947-7212
José Luis Aguirre-NoyolaCentro Nacional de Recursos Genéticos-INIFAP, Boulevard de la Biodiversidad No. 400, Rancho las Cruces, Tepatitlán de Morelos 47600, Jalisco, Mexico.ORCID 0000-0002-9695-7901
Raúl BarbónInstituto de Biotecnología de las Plantas, Universidad Central "Marta Abreu" de Las Villas, Carretera a Camajuaní km 5.5, Santa Clara 54830, Villa Clara, Cuba.
Rafael Gómez-KoskyInstituto de Investigaciones de la Caña de Azúcar (INICA Villa Clara), Ranchuelo 10400, Villa Clara, Cuba.
Carlos AnguloImmunology & Vaccinology Group and Laboratorio Nacional CONAHCYT de Generación de Vacunas Veterinarias y Servicios de Diagnóstico (LNC-GVD), Centro de Investigaciones Biológicas del Noroeste, S.C., Av. Instituto Politécnico Nacional 195, Playa Palo de Santa Rita Sur, La Paz 23096, Baja California Sur, Mexico.ORCID 0000-0002-7965-1679

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Somatic embryogenesis (SE) is a morphogenetic pathway widely employed in the commercial micropropagation of plants. This route enables the generation of somatic embryos from somatic tissues, which give rise to complete (bipolar) plants that develop like zygotic embryos. SE can proceed via direct or indirect pathways, and both approaches have been adapted not only for large-scale clonal propagation but also for the regeneration of genetically modified plants. In this context, SE can be harnessed as a versatile platform for recombinant protein production, including vaccine antigens and therapeutic proteins, by combining plant tissue culture with genetic transformation strategies. Successful examples include non-model plants, as

Indexed as

genetic transformationimmunizationin vitro cultureplant regenerationvaccination

Identifiers

PMID41440172
PMCPMC12730732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.