Evidence map›Paper›PMID 41440103›Full record

ArticleBrain sciences2025

Prevalence of Neurocognitive Disorders in the Elderly Quechua Population Using the Q-RUDAS.

Jonathan Zegarra-Valdivia, Ruth Diana Mamani Quispe, José Chinoapaza Turpo, Carmen Paredes-Manrique, Marco Malaga, Oscar Mamani-Benito, Rosa Montesinos, Nilton Custodio, Giuseppe Tosto

Abstract read
In one paragraph

Article in Brain sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jonathan Zegarra-ValdiviaPsychology Program, Faculty of Health Sciences, Universidad Cientifica del Sur, Lima 15842, Peru.ORCID 0000-0003-0497-5270
Ruth Diana Mamani QuispeEscuela Profesional de Psicología, Universidad Peruana Unión, Puno 21000, Peru.
José Chinoapaza TurpoEscuela Profesional de Psicología, Universidad Peruana Unión, Puno 21000, Peru.
Carmen Paredes-ManriqueFacultad de Psicología, Universidad Tecnológica del Perú, Lima 15046, Peru.
Marco MalagaUnidad de Investigación, Instituto Peruano de Neurociencias, Lima 15046, Peru.
Oscar Mamani-BenitoPsychology Deparment, Universidad Señor de Sipán, Chiclayo 14001, Peru.ORCID 0000-0002-9818-2601
Rosa MontesinosUnidad de Investigación, Instituto Peruano de Neurociencias, Lima 15046, Peru.
Nilton CustodioUnidad de Investigación, Instituto Peruano de Neurociencias, Lima 15046, Peru.ORCID 0000-0002-8025-3272
Giuseppe TostoTau Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.ORCID 0000-0001-7075-8245

Funding

Genetic and environmental risk factors in mestizos and indigenous populations of Peru: the role of Native component in Alzheimer's diseaseR56AG069118 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI TOSTO, GIUSEPPE · 2020 to 2020
$1.1M
Instituto Peruano de Neurociencias IPN00NIA NIH HHS R56 AG069118Universidad Señor de Sipán US2024-01
6 · The paper itself

Abstract

backgroundThe Rowland Universal Dementia Assessment Scale (RUDAS) is a validated cognitive screening tool for illiterate and low-educated individuals, adaptable across languages and cultures. In Peru, we adapted it for Quechua speakers (Q-RUDAS) to assess cognitive status in older adults.

objectiveWe aimed to estimate the prevalence of neurocognitive disorders-mild cognitive impairment (MCI) and dementia-among Quechua-speaking older adults in one of the most socially vulnerable districts of Peru using the Quechua version of the Rowland Universal Dementia Assessment Scale (Q-RUDAS), a brief cognitive screening tool validated in Peru.

methodsWe studied 511 participants from Puno a region in the southern Peruvian Andes (mean age 65.04 ± 6.73 years; 80.4% females), collecting sociodemographic data and Q-RUDAS scores. After excluding 18 individuals with medical conditions that could affect cognitive performance, such as neurological, psychiatric, or cerebrovascular disorders, 493 completed the test.

resultsAll Q-RUDAS items were well understood, although over 50% of participants struggled with visuospatial construction. The mean Q-RUDAS score was 26.01 ± 2.71. Of the participants, 446 (90.5%) scored within normal ranges (26.67 ± 1.92), 41 (8.3%) were classified as having mild cognitive impairment (MCI) (21.49 ± 1.92), and 6 (1.2%) as having dementia (17.00 ± 2.71) based on established Q-RUDAS cut-offs. Urban participants scored higher. The prevalence of MCI and dementia combined was 9.52%.

conclusionsThe Q-RUDAS is a culturally sensitive tool that can support the identification of cognitive impairment in Indigenous populations. Our findings highlight the need for further cross-validation studies to refine diagnostic accuracy in Quechua-speaking populations.

Indexed as

cognitive impairmentdementianeurocognitive disordersQ-RUDASquechua population

Identifiers

PMID41440103
PMCPMC12730204

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.