Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
10 authors.
Filipe F Stoyell-ContiDeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Alexander M KaiserDeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Miguel G RojasDeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Yuntao WeiDeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Matthew S SussmanDeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Juan S Lopez-McCormickDeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, USA.ORCID 0000-0003-1987-5555
Marwan TabbaraDeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Xiaofeng YangDepartment of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Roberto I Vazquez-PadronDeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, USA.ORCID 0000-0002-9370-276X
Laisel MartinezDeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, USA.ORCID 0000-0002-3009-8761
Funding
The Vascular Fibroblast: An Understudied Culprit In Postoperative Venous StenosisR01DK144860 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MARTINEZ, LAISEL · 2025 to 2025
$2.8M
The Role of Vascular Calprotectin in Arteriovenous Fistula MaturationR01DK132888 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Roberto Irenardo Vazquez Padron · 2022 to 2026
$2.1M
Integrin Activation to Prevent Early Arteriovenous Fistula Failure in End-stage Renal Disease PatientsR01DK136297 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI VINEET GUPTA, YAN-TING E. SHIU · 2024 to 2026
$1.5M
The importance of Lysyl Oxidase in AtherosclerosisF32HL158216 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI STOYELL-CONTI, FILIPE FERNANDES · 2021 to 2024
$246k
BLRD VA I01 BX006080BLRD VA IK6 BX006823NHLBI NIH HHS F32 HL158216NIDDK NIH HHS R01 DK132888NIDDK NIH HHS R01 DK136297NIDDK NIH HHS R01 DK144860NIH HHS 1R01DK144860-01NIH HHS 5F32HL158216-03NIH HHS 5R01DK132888-04NIH HHS 5R01DK136297-02United States Department of Veterans Affairs I01-BX006080United States Department of Veterans Affairs IK6-BX006823
6 · The paper itself
Abstract
The mouse carotid-jugular arteriovenous fistula (AVF) is a widely adopted surgical model to study venous remodeling after AVF creation. Despite its increasing use, the extent to which this model recapitulates the cellular and molecular remodeling processes observed in humans remains uncertain, which is essential for validating its translational relevance. Using bulk and single-cell RNA sequencing, we have depicted the transcriptional and cellular evolution of the mouse jugular vein after AVF anastomosis. Global transcriptomic profiling revealed that venous remodeling begins with a robust inflammatory response, followed by a prominent extracellular matrix (ECM) remodeling phase that peaks at postoperative day 10. Single-cell analyses confirmed the role of macrophage (3-fold) and neutrophil infiltration (12-fold) in sustaining the onset of venous remodeling. These monocytes/macrophages exhibited marked upregulation of pro-inflammatory and pro-fibrotic genes, including
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Sequential Inflammatory and Matrisome Programs Drive Remodeling of the Mouse Carotid-Jugular Arteriovenous Fistula. · full record | OpenQuestion