Evidence map›Paper›PMID 41439984›Full record

ReviewCells2025

MTAP-Null Tumors: A Comprehensive Review on Synthetic Vulnerabilities and Therapeutic Strategies.

Bavani Subramaniam, Wai Chin Chong, Aylar Babaei, Miriam Bornhorst, Chunchao Zhang, Roger Packer, Javad Nazarian

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Lessons from Cohort Studies of Targetable Metabolic Deficiencies in Lung Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bavani SubramaniamBrain Tumor Institute, Center for Cancer and Immunology Research, Children's National Hospital, Washington, DC 20012, USA.ORCID 0009-0000-9667-7742
Wai Chin ChongBrain Tumor Institute, Center for Cancer and Immunology Research, Children's National Hospital, Washington, DC 20012, USA.ORCID 0000-0002-7686-5559
Aylar BabaeiBrain Tumor Institute, Center for Cancer and Immunology Research, Children's National Hospital, Washington, DC 20012, USA.ORCID 0009-0004-0139-2605
Miriam BornhorstNorthwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
Chunchao ZhangBrain Tumor Institute, Center for Cancer and Immunology Research, Children's National Hospital, Washington, DC 20012, USA.
Roger PackerBrain Tumor Institute, Center for Cancer and Immunology Research, Children's National Hospital, Washington, DC 20012, USA.
Javad NazarianChildren's Research Center, University Children's Hospital Zurich, 8008 Zurich, Switzerland.ORCID 0000-0002-1951-9828

Funding

Gilbert Family Foundation 00003628
6 · The paper itself

Abstract

Homozygous deletion of the 9p21.3 genomic locus spanning the

Indexed as

NeoplasmsPurine-Nucleoside PhosphorylaseAnimalsHumansTumor Microenvironment5'-methylthioadenosine phosphorylasePurine-Nucleoside PhosphorylasecancerCDKN2Ametabolismmethylthioadenosine phosphorylasetherapy

Identifiers

PMID41439984
PMCPMC12732168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.