Evidence map›Paper›PMID 41439978›Full record

ReviewCells2025

Predicted Role of Mitsugumin 23 in Skeletal and Cardiac Muscle.

Daiki Watanabe, Richard C Edel, Miyuki Nishi, Hiroshi Takeshima, Samantha J Pitt

Abstract readReview
In one paragraph

Review in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daiki WatanabeGraduate School of Sport and Health Sciences, Osaka University of Health and Sport Sciences, Osaka 590-0496, Japan.ORCID 0000-0002-1278-3773
Richard C EdelSchool of Medicine, University of St Andrews, St Andrews KY16 9TF, UK.ORCID 0009-0008-4525-3788
Miyuki NishiGraduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan.
Hiroshi TakeshimaGraduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan.
Samantha J PittSchool of Medicine, University of St Andrews, St Andrews KY16 9TF, UK.ORCID 0000-0003-2257-1595

Funding

BBSRC funded EastBio studentship BB/T00875X/1Japan Society for the Promotion of Science 20K10634Japan Society for the Promotion of Science 21H02663Japan Society for the Promotion of Science 23K24738Japan Society for the Promotion of Science 23KK0297
6 · The paper itself

Abstract

Mitsugumin 23 (MG23) is a transmembrane protein expressed in the nuclear membrane and endo/sarcoplasmic reticulum (ER/SR) of various tissues, including skeletal and cardiac muscle. MG23 is a non-selective cation channel that has been implicated in the leakage of calcium ions (Ca

Indexed as

Membrane ProteinsMuscle, SkeletalMyocardiumAnimalsCalciumHumansSarcoplasmic ReticulumCalciumMembrane Proteinscalcium regulationMitsugumin23/TMEM109sarcoplasmic reticulum

Identifiers

PMID41439978
PMCPMC12732242

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.