Evidence map›Paper›PMID 41439605›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2026

Degenerative Changes in the Essential Tremor Cerebellum.

Elan D Louis, Phyllis L Faust

Abstract readLetter
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Elan D LouisDepartment of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID https://orcid.org/0000-0003-2062-362X
Phyllis L FaustDepartment of Pathology and Cell Biology, Columbia University Irving Medical Center and the New York Presbyterian Hospital, New York, New York, USA.ORCID https://orcid.org/0000-0001-6533-7921

Funding

Clinical Pathological Study of Cognitive Impairment in Essential TremorR01NS086736 · NINDS · YALE UNIVERSITY · PI COSENTINO, STEPHANIE ANN, LOUIS, ELAN D · 2014 to 2023
$8.1M
Deep Dive: Mapping the Neuropathology of Essential Tremor and Exploring the Molecular Underpinnings of NeurodegenerationR01NS117745 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FAUST, PHYLLIS L, LOUIS, ELAN D · 2021 to 2025
$4.7M
Targeting Cerebellar Endoplasmic Reticulum Calcium Handling in Essential TremorR01NS124854 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PHYLLIS L FAUST, Sheng-Han Kuo · 2022 to 2026
$2.9M
Positron Emission Tomography (PET)-Derived Measurement of Brain Synaptic Vesicle Glycoprotein 2A (SV2A) – a Potential Biomarker in Patients with Essential TremorR01NS137042 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI ELAN D LOUIS, DAVID A MATUSKEY · 2025 to 2026
$1.3M
Developing Purkinje Cell Synaptic Therapies to Restore Circuit Function in Cerebellar DegenerationR01NS136686 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Sheng-Han Kuo · 2025 to 2026
$1.2M
UT Southwestern Advancement of Neuroscience Research Careers (UTSWANS)UE5NS098987 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI ELAN D LOUIS, NADER POURATIAN · 2024 to 2026
$177k
NIH HHS R01 NS117745NINDS NIH HHS R01 NS086736NINDS NIH HHS R01 NS117745NINDS NIH HHS R01 NS124854NINDS NIH HHS R01 NS136686NINDS NIH HHS R01 NS137042NINDS NIH HHS UE5 NS098987
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41439605
PMCPMC12945392

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.