Evidence map›Paper›PMID 41439251›Full record

ArticleJournal of bone oncology2025

Rotationplasty performed in adults versus minors: a comparative study of long-term quality of life, functional and biomechanical outcomes.

Gitte G J Krebbekx, N F J Waterval, M A Brehm, M J C Duivenvoorden, I N Sierevelt, J A M Bramer, G M M J Kerkhoffs, F G M Verspoor

Abstract read
In one paragraph

Article in Journal of bone oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gitte G J KrebbekxDepartment of Orthopedic Surgery and Sports Medicine, Amsterdam UMC, Amsterdam Movement Sciences, University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands.
N F J WatervalDepartment of Rehabilitation Medicine, Amsterdam University Medical Center, Meibergdreef 9, Amsterdam, the Netherlands.
M A BrehmDepartment of Rehabilitation Medicine, Amsterdam University Medical Center, Meibergdreef 9, Amsterdam, the Netherlands.
M J C DuivenvoordenDepartment of Orthopedic Surgery and Sports Medicine, Amsterdam UMC, Amsterdam Movement Sciences, University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands.
I N SiereveltDepartment of Orthopedic Surgery and Sports Medicine, Amsterdam UMC, Amsterdam Movement Sciences, University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands.
J A M BramerDepartment of Orthopedic Surgery and Sports Medicine, Amsterdam UMC, Amsterdam Movement Sciences, University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands.
G M M J KerkhoffsDepartment of Orthopedic Surgery and Sports Medicine, Amsterdam UMC, Amsterdam Movement Sciences, University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands.
F G M VerspoorDepartment of Orthopedic Surgery and Sports Medicine, Amsterdam UMC, Amsterdam Movement Sciences, University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Rotationplasty is a surgical technique primarily used in pediatric patients with malignant bone tumors around the knee. Its application in adults is rare, and outcomes are poorly defined. This study aimed to compare long-term QoL, function, and gait between patients treated with rotationplasty in childhood versus adulthood. Methods: This cross-sectional post-hoc predefined secondary analysis included 33 patients treated between 1980-2002 (9 adults, 24 minors). Assessments included the mental and physical component score of the Short Form-36 (SF-36, MCS/ PCS), overall satisfaction, radiographs (Kellgren-Lawrence) of the pseudo-knee, contralateral ankle, and hips, Toronto Extremity Salvage Score (TESS), Musculoskeletal Tumor Society Score (MSTS), energy cost of comfortable walking during a 6-minute walk test, and 3-Dimenional gait analysis. Group comparisons were performed across all outcomes. Additionally, a systematic literature search identified published adult cases. Results: People who underwent surgery during adulthood reported significantly higher physical QoL compared to those operated in childhood (MD 6.1, 95 % CI 0.0-12.3; Conclusion: Adults who undergo rotationplasty can achieve long-term quality of life, functional, and gait outcomes at least comparable to those operated on in childhood. These findings suggest that rotationplasty may be a viable reconstructive option in adults.

Indexed as

AdultsRotationplastySarcomaTumor

Identifiers

PMID41439251
PMCPMC12719068

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.