Evidence map›Paper›PMID 41439023›Full record

ArticleComputational and structural biotechnology journal2025

StructRMDB: A database of RNA modification sites that affect RNA secondary structure.

Ziyan Zhang, Xuan Wang, Jingxian Zhou, Jia Meng, Bowen Song, Yuxin Liang, Yuheng Cai, Jiongming Ma

Abstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. ProNA3D: Distance-Based Analysis of Nucleic Acid-Containing Interfaces.Computational and structural biotechnology journal · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ziyan ZhangDepartment of Biosciences and Bioinformatics, Xi'an Jiaotong-Liverpool University, Suzhou, Jiangsu 215123, China.
Xuan WangDepartment of Biosciences and Bioinformatics, Xi'an Jiaotong-Liverpool University, Suzhou, Jiangsu 215123, China.
Jingxian ZhouSino-French Hoffmann Institute, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, Guangdong 511436, China.
Jia MengDepartment of Biosciences and Bioinformatics, Xi'an Jiaotong-Liverpool University, Suzhou, Jiangsu 215123, China.
Bowen SongDepartment of Public Health, School of Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Yuxin LiangDepartment of Biosciences and Bioinformatics, Xi'an Jiaotong-Liverpool University, Suzhou, Jiangsu 215123, China.
Yuheng CaiDepartment of Biosciences and Bioinformatics, Xi'an Jiaotong-Liverpool University, Suzhou, Jiangsu 215123, China.
Jiongming MaDepartment of Biosciences and Bioinformatics, Xi'an Jiaotong-Liverpool University, Suzhou, Jiangsu 215123, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-transcriptional RNA modifications, prevalent in multiple RNA species such as mRNA, rRNA, and tRNA, play a significant role in biological processes by altering RNA structures. With recent advancements in prediction algorithms, it is possible to predict RNA secondary structure for sequences containing modified bases. In this study, we introduce StructRMDB, the first database designed to characterize the impact of chemical modifications on RNA secondary structure. StructRMDB comprises more than 880,000 RNA modification sites and their structural impacts, including

Indexed as

Adenosine-to-inosine editingN6-methyladenosinePseudouridineRNA modificationRNA secondary structure

Identifiers

PMID41439023
PMCPMC12720313

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.