Evidence map›Paper›PMID 41438881›Full record

ArticleJPRAS open2026

Enhancing microvascular anastomoses with the Synovis Coupler device: A retrospective analysis of management of vascular diameter discrepancies.

Sergio Razzano, Carlo Petroccione, Domenico Mariniello, Marcello Molle, Francesca La Torre, Ilaria Mataro, Vincenzo Manfellotto

Abstract readCase Reports
In one paragraph

Article in JPRAS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sergio RazzanoDepartment of Plastic and Reconstructive Surgery and Burn Unit, Hospital A. Cardarelli, Naples, Italy.
Carlo PetroccioneDepartment of Plastic and Reconstructive Surgery and Burn Unit, Hospital A. Cardarelli, Naples, Italy.
Domenico MarinielloDepartment of Plastic, Reconstructive, Aesthetic Surgery, Section of Plastic, Reconstructive, Aesthetic Surgery, Department of Public Health, Federico II University, Naples, Italy.
Marcello MolleMultidisciplinary Department of Medical-Surgical and Dental Specialties, Plastic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples 80138, Italy.
Francesca La TorreDepartment of Plastic and Reconstructive Surgery and Burn Unit, Hospital A. Cardarelli, Naples, Italy.
Ilaria MataroDepartment of Plastic and Reconstructive Surgery and Burn Unit, Hospital A. Cardarelli, Naples, Italy.
Vincenzo ManfellottoDepartment of Plastic and Reconstructive Surgery and Burn Unit, Hospital A. Cardarelli, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Introduction: Microvascular surgery enables complex tissue repairs with free flaps. The Synovis Coupler has streamlined venous anastomoses, improving speed and precision. However, size discrepancies between donor and recipient vessels continue to cause postoperative complications. This study presents our experience in managing caliber discrepancies, optimizing venous flow, reducing thrombosis risk, and improving free flap survival. Material and Methods: This retrospective observational study analyzed data from patients undergoing free flap reconstruction between January 2018 and January 2024. A total of 84 microvascular free tissue transfers and 86 venous anastomoses were performed using a mechanical coupler system. Results: Eighty-six venous anastomoses were completed, averaging 3.25 min each, with an average coupler size of 2.34 mm. No postoperative returns to the operating room or anastomosis revisions were required. Complications included one infection and one hematoma, both resulting in flap necrosis. The average follow-up was 1.7 years, with no cases of venous ischemia. Discussion and Conclusion: Our experience suggests that adapting the vessel lumen may represent a practical option for managing diameter discrepancies when using couplers. The approach appeared to reduce the need for grafts and allowed efficient anastomosis. However, the retrospective design, limited sample size, and lack of a comparative group constrain the strength of these findings. Further prospective studies are warranted to confirm whether this method offers a consistent advantage over established techniques.

Indexed as

Free flapMechanical anastomosisMicrovascular anastomosisReconstructive microsurgeryVein diameter discrepancy

Identifiers

PMID41438881
PMCPMC12719696

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.