ArticleComprehensive psychoneuroendocrinology2025
Before pregnancy trauma primes oxytocin receptor expression in placenta during superstorm sandy.
Article in Comprehensive psychoneuroendocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Given the role of sympathetic nervous system and hypothalamic-pituitary-adrenal (HPA) axis in trauma transmission and oxytocin's stress buffering effects, this study examined whether placental oxytocin receptor ( Methods: A sample (N = 152) was drawn from a longitudinal birth cohort. Results: In the proportion of samples with detectable Conclusion: Given oxytocin linked placental adaptations to cope with consequences of stress, this greater-than-additive modification, as evidenced by the synergy index, suggests trauma exposure before pregnancy fundamentally changes how the placenta responds to disaster exposure during pregnancy in anticipation of harsh external conditions.
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