Harnessing nanozyme-immunomodulation for antiviral defense via Fe-nordihydroguaiaretic acid nano-networks.

Hongping Wan, Zhengqun Huang, Mingrun Tang, Huirong Tan, Kai Deng, Yingnan Liu, Xinghong Zhao, Hongjun Chen

Abstract read

In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hongping WanCenter for Infectious Diseases Control (CIDC), Sichuan Agricultural University, Chengdu, 611130, China.

Zhengqun HuangCenter for Infectious Diseases Control (CIDC), Sichuan Agricultural University, Chengdu, 611130, China.

Mingrun TangCenter for Infectious Diseases Control (CIDC), Sichuan Agricultural University, Chengdu, 611130, China.

Huirong TanCenter for Infectious Diseases Control (CIDC), Sichuan Agricultural University, Chengdu, 611130, China.

Kai DengCenter for Infectious Diseases Control (CIDC), Sichuan Agricultural University, Chengdu, 611130, China.

Yingnan LiuState Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.

Xinghong ZhaoCenter for Infectious Diseases Control (CIDC), Sichuan Agricultural University, Chengdu, 611130, China.

Hongjun ChenState Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enveloped viruses such as coronaviruses are highly transmissible, necessitating effective prevention and inactivation strategies. In this study, we engineered uniform, small-sized (∼57 nm) iron-phenolic nano-networks (NA-Fe) that exhibit high lipoxidase-like activity for the inactivation of enveloped virus, encompassing both DNA virus (Pseudorabies, PRV) and RNA virus (Transmissible Gastroenteritis, TGEV; and Porcine epidemic diarrhea virus, PEDV). Theoretical studies indicate that NA-Fe facilitates the adsorption of pentadiene moieties within the viral envelope through interactions between the

Indexed as

Antiviral activityComprehensive biosecurityInnate immune responsesLipoxidase-like activityNA-Fe nano-networks

Identifiers

PMID41438709

DOI10.1016/j.mtbio.2025.102567

PMCPMC12719199

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.