ArticleGenetics research2025
A Cuproptosis-Related lncRNA Signature Predicts Prognosis and Shapes the Immune Landscape in Primary Lower-Grade Glioma.
Article in Genetics research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- A Cuproptosis-Related lncRNA Signature Predicts Prognosis and Shapes the Immune Landscape in Primary Lower-Grade Glioma.Genetics research · 2025Article
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Authors and funding
6 authors.
Funding
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Abstract
Glioma represents the most prevalent intracranial neoplasms. Lower-grade gliomas (LGGs) are an important subtype of glioma, but the risk stratification of LGG has not been fully elucidated. As a recently recognized form of programmed cell death, cuproptosis is intimately tied to mitochondrial metabolism. Moreover, investigations have revealed that cuproptosis has been implicated in tumor initiation and progression. Long noncoding RNAs (lncRNAs) are engaged in diverse biological processes and connected with the malignant phenotype of gliomas. However, the significance of cuproptosis-related lncRNAs (CRLs) in LGG development remains not fully elucidated. In this work, 963 CRLs were identified using correlation analysis, and a prognostic signature was constructed based on LASSO and multivariate Cox regression analyses. This signature comprised four CRLs:
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