Evidence map›Paper›PMID 41438599›Full record

ReviewClinical pharmacology : advances and applications2025

Research Progress on the Clinical Application of Remimazolam Outside the Operating Room: A Review of Pharmacological Characteristics, Clinical Effects, and Safety.

Hao Luo, Ce Zhou, YingDong Qu, Xin Kuang

Abstract readReview
In one paragraph

Review in Clinical pharmacology : advances and applications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hao LuoDepartment of Anesthesiology, People's Hospital of Longhua, Shenzhen, 518109, People's Republic of China.
Ce ZhouDepartment of Anesthesiology, People's Hospital of Longhua, Shenzhen, 518109, People's Republic of China.ORCID 0009-0008-7367-6294
YingDong QuDepartment of Anesthesiology, People's Hospital of Longhua, Shenzhen, 518109, People's Republic of China.
Xin KuangDepartment of Anesthesiology, People's Hospital of Longhua, Shenzhen, 518109, People's Republic of China.ORCID 0000-0002-3647-6524

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Remimazolam is a novel ultra-short-acting benzodiazepine sedative, which has shown great promise in clinical scenarios such as outpatient surgeries, endoscopic examinations, intensive care units, and emergency departments due to its rapid onset, adjustable sedation level, and fast metabolic clearance. Currently, there is no consensus on the clinical application of remimazolam in non-operating room anesthesia. This article provides a comprehensive overview of its pharmacological properties and metabolic characteristics, with a particular focus on its application in special populations such as the elderly, patients with high cardiovascular risk, and children. The main purpose is to evaluate its safety and sedative effect in non-operating room settings by comparing it with traditional sedatives, and to provide insights for future research directions, thereby offering theoretical basis and practical guidance for the rational clinical application of this drug outside the operating room.

Indexed as

clinical applicationoutside the operating roompharmacological characteristicsremimazolamsedationspecial populations

Identifiers

PMID41438599
PMCPMC12720940

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.