Evidence map›Paper›PMID 41438567›Full record

ArticleJournal of oral microbiology2025

Results of bacterial cultivation are infrequently utilized in the treatment of patients hospitalized with severe odontogenic infections - a retrospective cohort study.

Rasmus Søndenbroe, Merete Markvart, Daniel Belstrøm, Frederik Boëtius Hertz, Thomas Bjarnsholt, Claus Henrik Nielsen, Sanne Werner Møller Andersen, Simon Storgård Jensen

Abstract read
In one paragraph

Article in Journal of oral microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rasmus SøndenbroeDepartment of Odontology, Section of Oral Biology and Immunopathology, University of Copenhagen, Copenhagen N, Denmark.ORCID https://orcid.org/0009-0003-6533-4941
Merete MarkvartDepartment of Odontology, Section of Clinical Oral Microbiology, University of Copenhagen, Copenhagen N, Denmark.ORCID https://orcid.org/0000-0002-9524-9233
Daniel BelstrømDepartment of Odontology, Section of Clinical Oral Microbiology, University of Copenhagen, Copenhagen N, Denmark.ORCID https://orcid.org/0000-0001-7116-5388
Frederik Boëtius HertzDepartment of Clinical Microbiology, Copenhagen University Hospital, Copenhagen N, Denmark.ORCID https://orcid.org/0000-0003-0888-4616
Thomas BjarnsholtDepartment of Clinical Microbiology, Copenhagen University Hospital, Copenhagen N, Denmark.ORCID https://orcid.org/0000-0002-8003-7414
Claus Henrik NielsenDepartment of Odontology, Section of Oral Biology and Immunopathology, University of Copenhagen, Copenhagen N, Denmark.ORCID https://orcid.org/0000-0001-7543-9016
Sanne Werner Møller AndersenDepartment of Oral and Maxillofacial Surgery, Copenhagen University Hospital, Copenhagen N, Denmark.ORCID https://orcid.org/0000-0001-9016-2895
Simon Storgård JensenDepartment of Odontology, Section of Oral Biology and Immunopathology, University of Copenhagen, Copenhagen N, Denmark.ORCID https://orcid.org/0000-0002-3519-4103

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients hospitalized with severe odontogenic infections (SOI) receive empiric intravenous antibiotics. Microbiological cultivation and antibiotic susceptibility testing are commonly performed, although the clinical value is debated. Objective: To assess the value of routine microbiological cultivation and susceptibility testing in patients hospitalized with SOI. Design: This retrospective cohort study included patients hospitalized with SOI, at the University Hospital of Copenhagen, Denmark, from November 2012 to 2019. Data on microbiological cultivation, bacterial identification and antibiotic susceptibility testing were obtained from hospital records. Statistical analysis included χ² test, Fisher's exact test, analysis of variance and logistic regression. Results: A total of 384 patients were included, with microbiological data available for 243 patients. Antibiotic treatment was modified in 47 patients and in seven cases, the modification was based on cultivation and antibiotic susceptibility testing. Higher age was associated with the need for cultivation and susceptibility testing ( Conclusion: Testing rarely influences antibiotic management in SOI. Higher age showed limited predictive value. The high prevalence of penicillin resistance among patients with SOI warrants further investigation.

Indexed as

anti-bacterial agents/pharmacologyanti-bacterial agents/therapeutic usebacterial infections/diagnosisdrug resistanceMouth diseases/microbiologytooth diseases/drug therapytooth diseases/microbiology

Identifiers

PMID41438567
PMCPMC12720675

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.