Evidence map›Paper›PMID 41438512›Full record

ArticleFrontiers in pharmacology2025

Selective cytotoxicity of

Alejandro Madrid, Valentina Silva, Alessandra Russo, Alejandra Catalina Moller, Elizabeth Sánchez, Joan Villena, Carlos Jara-Gutiérrez, Iván Montenegro

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Chemical Profile and Bioinsecticidal Nanoemulsion ofPlants (Basel, Switzerland) · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alejandro MadridLaboratorio de Productos Naturales y Síntesis Orgánica (LPNSO), Facultad de Ciencias Naturales y Exactas, Universidad de Playa Ancha, Valparaíso, Chile.
Valentina SilvaLaboratorio de Productos Naturales y Síntesis Orgánica (LPNSO), Facultad de Ciencias Naturales y Exactas, Universidad de Playa Ancha, Valparaíso, Chile.
Alessandra RussoDepartment of Drug and Health Sciences, University of Catania, Catania, Italy.
Alejandra Catalina MollerEscuela de Tecnología Médica, Facultad de Medicina, Universidad de Valparaíso, Viña del Mar, Chile.
Elizabeth SánchezCentro de Biotecnología, Universidad Técnica Federico Santa María, Valparaiso, Chile.
Joan VillenaCenter of Interdisciplinary Biomedical and Engineering Research for Health (MEDING), Escuela de Medicina, Facultad de Medicina, Universidad de Valparaíso, Viña del Mar, Chile.
Carlos Jara-GutiérrezCenter of Interdisciplinary Biomedical and Engineering Research for Health (MEDING), Escuela de Kinesiología, Facultad de Medicina, Universidad de Valparaíso, Valparaíso, Chile.
Iván MontenegroMillennium Nucleus Bioproducts, Genomics and Environmental Microbiology (BioGEM), Valparaíso, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is a leading cause of mortality worldwide, prioritizing the search for new therapies with improved toxicity profiles. Natural products, such as essential oils (EOs), are a valuable source of potential chemotherapeutic agents.

Indexed as

apoptosiscytotoxic activityditerpenesessential oilGomortega keule

Identifiers

PMID41438512
PMCPMC12719474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.