Evidence map›Paper›PMID 41438238›Full record

ArticleLancet regional health. Americas2026

Rapid weight gain in first 2 years of life and BMI trajectories from 3 to <10 years: a population-based longitudinal study of 1.7 million Brazilian children.

Carolina Santiago-Vieira, Leah Li, Rita de Cássia Ribeiro Silva, Juliana Freitas de Mello E Silva, Enny S Paixão, Maurício L Barreto, Gustavo Velasquez-Melendez

Abstract read
In one paragraph

Article in Lancet regional health. Americas, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carolina Santiago-VieiraSchool of Nursing, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Leah LiPopulation, Policy and Practice Research and Teaching Department, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.
Rita de Cássia Ribeiro SilvaCenter of Data and Knowledge Integration for Health (CIDACS), Fiocruz-Bahia, Salvador, Brazil.
Juliana Freitas de Mello E SilvaCenter of Data and Knowledge Integration for Health (CIDACS), Fiocruz-Bahia, Salvador, Brazil.
Enny S PaixãoCenter of Data and Knowledge Integration for Health (CIDACS), Fiocruz-Bahia, Salvador, Brazil.
Maurício L BarretoCenter of Data and Knowledge Integration for Health (CIDACS), Fiocruz-Bahia, Salvador, Brazil.
Gustavo Velasquez-MelendezSchool of Nursing, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Obesity is considered a disease with negative health impacts at all life stages. Changes in growth patterns, such as postnatal rapid weight gain (RWG), can be important predictors of growth trajectories in children. We investigated the association between RWG during the first two years of life and subsequent BMI trajectories from the age 3-to 9 years, and whether the association differed by birth weight group. Methods: We used the data of a population-based cohort from the Cadastro Único (CadÚnico) of the Federal Government, the linkage of the National Live Births System (SINASC) and the National Food and Nutritional Surveillance System (SISVAN). The sample comprised 1.7 million Brazilian children aged from zero to nine years from 2008 to 2017. Mixed-effects models were used to estimate mean age-trajectories for BMI by RWG group. Findings: Children who experienced RWG during the first two years of life had higher mean BMI trajectories from 3 to 9 years, compared to those who did not. The difference was seen across all birth weight groups, and was more evident for the children with high birth weight. At age 9, the BMI difference between RWG and non-RWG children was 1.31 kg/m Interpretation: Children who experienced RWG during the first two years of life had higher BMI trajectories than children who did not. The finding highlighted the importance of monitoring child growth, which allows the early identification of potential growth deviations and the implementation of necessary interventions to ensure that children grow healthy and reach their full developmental potential. Funding: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior-CAPES, CAPES/Print/UFBA; University College London (UCL); National Institute for Health Research (NIHR) Great Ormond Street Hospital Biomedical Research Centre; Fundação de Amparo à Pesquisa do Estado de Minas Gerais-FAPEMIG; National Council for Scientific and Technological Development-CNPq; CNPq/CGFP/DECIT/SECTICS; Departamento de Ciência e Tecnologia da Secretaria de Ciência, Tecnologia, Inovação e Complexo da Saúde do Ministério da Saúde; Wellcome Trust.

Indexed as

Birth weightBody mass indexGrowth trajectoriesRapid weight gain

Identifiers

PMID41438238
PMCPMC12719978

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.