Evidence map›Paper›PMID 41438200›Full record

ArticleAnalytical cellular pathology (Amsterdam)2025

Apoptosis, Cell Cycle and Differentiation Effects of Propolis Extracted in Olive Oil on HL-60 AML Cells: A Flow Cytometric Analysis.

Hamide Dogan, A Ata Ozcimen, Erkan Alabas, Sibel Silici, Yasemin Saygideger, Birgul Ozdemir

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical cellular pathology (Amsterdam), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hamide DoganDepartment of Translational Medicine, Institute of Health Sciences, Cukurova University, Adana, Türkiye, cu.edu.tr.ORCID https://orcid.org/0000-0002-6002-6013
A Ata OzcimenDepartment of Biology, Faculty of Sciences, Mersin University, Mersin, Türkiye, mersin.edu.tr.ORCID https://orcid.org/0000-0002-8871-8943
Erkan AlabasDepartment of Biology, Faculty of Sciences, Mersin University, Mersin, Türkiye, mersin.edu.tr.ORCID https://orcid.org/0000-0001-8145-452X
Sibel SiliciAgricultural Biotechnology Department, Seyrani Faculty of Agriculture, Erciyes University, Kayseri, Türkiye, erciyes.edu.tr.ORCID https://orcid.org/0000-0003-2810-2917
Yasemin SaygidegerDepartment of Translational Medicine, Institute of Health Sciences, Cukurova University, Adana, Türkiye, cu.edu.tr.ORCID https://orcid.org/0000-0003-3293-373X
Birgul OzdemirDepartment of Biology, Faculty of Sciences, Mersin University, Mersin, Türkiye, mersin.edu.tr.ORCID https://orcid.org/0000-0001-7835-2143

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, researchers have focused on the drug capacity of natural products and their components with low side effects in the treatment of leukemia. This study aims to elucidate the antileukemic mechanism of action of olive oil extract of propolis (OEP) together with methylprednisolone (MP) in HL-60 cells, an acute myeloid leukemia cell line. The WST-8 kit was used to test the cytotoxic and proliferative effects of OEP on HL-60 cells. Flow cytometry was additionally applied for determining apoptotic status, cell cycle, and differentiation levels (CD11b, CD14, and CD68). The IC

Indexed as

ApoptosisCell CycleCell DifferentiationFlow CytometryLeukemia, Myeloid, AcuteOlive OilPropolisCell Cycle CheckpointsCell ProliferationHL-60 CellsHumansMethylprednisoloneMethylprednisoloneOlive OilPropolisapoptosisdifferentiationDNA cell cycleolive oil extract of propolis

Identifiers

PMID41438200
PMCPMC12721472

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.