ArticleFrontiers in medicine2025
Enhanced surgical outcomes in refractory glaucoma: a retrospective study of using adjustable sutures with Ex-PRESS filtration device.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: Evaluate the clinical efficacy of combining adjustable sutures with the Ex-PRESS Glaucoma Filtration Device in patients with refractory glaucoma, with an emphasis on controlling intraocular pressure (IOP) and reducing postoperative complications. Methods: This retrospective cohort study involved refractory glaucoma patients treated at Jinan Second People's Hospital between January 2023 and October 2024. Patients were divided into two groups: one received standard Ex-PRESS implantation (control), and the other received Ex-PRESS implantation with adjustable sutures (experimental). Outcomes included IOP, best-corrected visual acuity (BCVA), filtering bleb morphology, and postoperative complications, assessed over a 6-month follow-up. Results: The two groups included 75 patients (75 eyes), with 38 (38 eyes) in the experimental group and 37 (37 eyes) in the control group. Both groups showed significant postoperative IOP reduction. The experimental group had higher IOP on Day 1 but significantly lower IOP at all subsequent time points (Week 1 to 6 months, Conclusion: The addition of adjustable sutures to Ex-PRESS implantation offers superior IOP control, promotes the formation of functioning bleb, and reduces postoperative complications in refractory glaucoma. This technique provides a promising refinement to existing surgical strategies. Further prospective studies are warranted to confirm long-term benefits.
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