Evidence map›Paper›PMID 41438094›Full record

ArticleiScience2025

Metabolic silencing induced by the small bacterial membrane protein YohP.

Ana Natriashvili, Nahid Mohammadsadeghi, Martin Milanov, Eva Smudde, Isabel Prucker, Henning J Jessen, Iulia Carabadjac, Heiko Heerklotz, Pedro H C Franco, Julian D Langer and 1 more

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ana NatriashviliInstitute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, Albert-Ludwigs-University Freiburg, 79104 Freiburg, Germany.
Nahid MohammadsadeghiInstitute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, Albert-Ludwigs-University Freiburg, 79104 Freiburg, Germany.
Martin MilanovInstitute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, Albert-Ludwigs-University Freiburg, 79104 Freiburg, Germany.
Eva SmuddeInstitute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, Albert-Ludwigs-University Freiburg, 79104 Freiburg, Germany.
Isabel PruckerInstitute for Organic Chemistry, Faculty of Chemistry and Pharmacy, Albert-Ludwigs-University Freiburg, 79104 Freiburg, Germany.
Henning J JessenInstitute for Organic Chemistry, Faculty of Chemistry and Pharmacy, Albert-Ludwigs-University Freiburg, 79104 Freiburg, Germany.
Iulia CarabadjacInstitute of Pharmaceutical Sciences, Faculty of Chemistry and Pharmacy, Albert-Ludwigs-University Freiburg, 79104 Freiburg, Germany.
Heiko HeerklotzInstitute of Pharmaceutical Sciences, Faculty of Chemistry and Pharmacy, Albert-Ludwigs-University Freiburg, 79104 Freiburg, Germany.
Pedro H C FrancoMass Spectrometry and Proteomics, Max-Planck Institute for Biophysics, 60438 Frankfurt am Main, Germany.
Julian D LangerMass Spectrometry and Proteomics, Max-Planck Institute for Biophysics, 60438 Frankfurt am Main, Germany.
Hans-Georg KochInstitute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, Albert-Ludwigs-University Freiburg, 79104 Freiburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small membrane proteins represent an abundant and ubiquitous class of proteins that are often up-regulated when cells encounter unfavorable conditions, yet their function remains poorly understood. In bacteria, these proteins consist of typically less than 50 amino acids, without detectable catalytic activity. Thus, the benefit of producing these proteins during stress conditions is unknown. In the current study we used a multidisciplinary approach to determine the function of the 27-amino-acid-long protein YohP in

Indexed as

Cell biologyMembrane architectureMicrobiology

Identifiers

PMID41438094
PMCPMC12719787

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.