Evidence map›Paper›PMID 41438076›Full record

ArticleiScience2025

Synergistic immunomodulatory effects of naringenin and photothermal therapy in triple-negative breast cancer.

Chunyu Lei, Yu Yao, Qian Xie, Na Li, Chenghao Zhu, Haomiao Lan, Sisi Yang, Gang Wang, Xianfeng Peng, Duwen Zheng and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chunyu LeiDepartment of Nuclear Medicine, Zigong First People's Hospital, Zigong Academy of Medical Sciences, Zigong 643000, China.
Yu YaoDepartment of Medical Ultrasound, Shanghai Tenth People's Hospital, Ultrasound Research and Education Institute, School of Medicine, Tongji University, Shanghai 200072, China.
Qian XieDepartment of Diagnostic Ultrasound, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430015, China.
Na LiDepartment of Ultrasonogrphy, Zigong Fouth People's Hospital, Zigong 643000, China.
Chenghao ZhuMedical Department, Wuhan City College, Wuhan 430083, China.
Haomiao LanDepartment of Thyroid & Breast Surgery, Zigong First People's Hospital, Zigong Academy of Medical Sciences, Zigong 643000, China.
Sisi YangDepartment of Thyroid & Breast Surgery, Zigong First People's Hospital, Zigong Academy of Medical Sciences, Zigong 643000, China.
Gang WangDepartment of Integrated Chinese and Western Medicine, Zigong First People's Hospital, Zigong Academy of Medical Sciences, Zigong 643000, China.
Xianfeng PengDepartment of Nuclear Medicine, Zigong First People's Hospital, Zigong Academy of Medical Sciences, Zigong 643000, China.
Duwen ZhengDepartment of Nuclear Medicine, Zigong First People's Hospital, Zigong Academy of Medical Sciences, Zigong 643000, China.
Haili WangDepartment of Nuclear Medicine, Zigong First People's Hospital, Zigong Academy of Medical Sciences, Zigong 643000, China.
Ke ZhuDepartment of Nuclear Medicine, Zigong First People's Hospital, Zigong Academy of Medical Sciences, Zigong 643000, China.
Ziyang ZhuDepartment of Nuclear Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu 610072, China.
Fuqiang ShaoDepartment of Nuclear Medicine, Zigong First People's Hospital, Zigong Academy of Medical Sciences, Zigong 643000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) represents a highly aggressive subtype with limited treatment options, primarily relying on chemotherapy. Emerging therapies, including photothermal therapy (PTT) and related combination therapies, are considered highly promising. Naringenin, a flavonoid glycoside with diverse biological activities, can enhance immune responses as well as inhibit cancer cell proliferation. We developed photothermal bovine serum albumin (BSA)-biomineralized MnO

Indexed as

biological sciencesbiomaterialscancerdrug delivery system

Identifiers

PMID41438076
PMCPMC12721143

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.