Evidence map›Paper›PMID 41438061›Full record

ArticleiScience2025

Marta L DeDiego, Raúl López-Fernández-Sobrino, Jordi Pedragosa, Darío López-García, Aitor Nogales, Jordi Durbán, Fernando Cardona, Laia Llucià-Carol, Vanessa Rivero, Paula Vazquez-Utrilla and 45 more

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. The FunctionalInternational journal of molecular sciences · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

55 authors.

Marta L DeDiegoDepartment of Molecular and Cell Biology, National Center for Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.
Raúl López-Fernández-SobrinoDepartment of Molecular and Cell Biology, National Center for Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.
Jordi PedragosaDepartment of Neuroscience and Experimental Therapeutics, Institute for Biomedical Research of Barcelona (IIBB-CSIC), Barcelona, Spain.
Darío López-GarcíaDepartment of Molecular and Cell Biology, National Center for Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.
Aitor NogalesCenter for Animal Health Research (CISA-INIA-CSIC), Madrid, Valdeolmos, Spain.
Jordi DurbánInstitute of Biomedicine of Valencia (IBV-CSIC), València, Spain.
Fernando CardonaInstitute of Biomedicine of Valencia (IBV-CSIC), València, Spain.
Laia Llucià-CarolDepartment of Neuroscience and Experimental Therapeutics, Institute for Biomedical Research of Barcelona (IIBB-CSIC), Barcelona, Spain.
Vanessa RiveroDepartment of Molecular and Cell Biology, National Center for Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.
Paula Vazquez-UtrillaDepartment of Molecular and Cell Biology, National Center for Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.
Laura Palomo Sanchez-GrandeDepartment of Molecular and Cell Biology, National Center for Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.
Miriam CoboInstituto de Física de Cantabria (IFCA-CSIC), Santander, Spain.
Lara LloretInstituto de Física de Cantabria (IFCA-CSIC), Santander, Spain.
Leonardo Márquez-KisinouskyDepartment of Neuroscience and Experimental Therapeutics, Institute for Biomedical Research of Barcelona (IIBB-CSIC), Barcelona, Spain.
Francisca Ruiz-JaénDepartment of Neuroscience and Experimental Therapeutics, Institute for Biomedical Research of Barcelona (IIBB-CSIC), Barcelona, Spain.
Francisco LozanoInstitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Oriol SibilaInstitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Rosa FanerInstitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Pedro CastroInstitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Carlos DomingoHospital Clínic de Barcelona, Barcelona, Spain.
Verónica RoblesHospital Clínic de Barcelona, Barcelona, Spain.
Josep L BediniHospital Clínic de Barcelona, Barcelona, Spain.
Verónica RicoHospital Clínic de Barcelona, Barcelona, Spain.
Daiana AgueroHospital Clínic de Barcelona, Barcelona, Spain.
Alex SorianoInstitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Andrea Martín NaldaPediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute (VHIR), Vall d'Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona (UAB), Barcelona, Catalonia, Spain.
Alba Parra MartínezPediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute (VHIR), Vall d'Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona (UAB), Barcelona, Catalonia, Spain.
Roger ColobranImmunology Division, Department of Clinical and Molecular Genetics, Hospital Universitari Vall d'Hebron (HUVH), Vall d'Hebron Research Institute, UAB, Barcelona, Catalonia, Spain.
Pere Soler-PalacínPediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute (VHIR), Vall d'Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona (UAB), Barcelona, Catalonia, Spain.
Alexandre Serra-LlovichHospital Universitari Mutua Terrassa, Terrasa, Spain.
Beatriz DietlHospital Universitari Mutua Terrassa, Terrasa, Spain.
M Jesús ArranzHospital Universitari Mutua Terrassa, Terrasa, Spain.
David DalmauHospital Universitari Mutua Terrassa, Terrasa, Spain.
Jaime Signes-CostaHospital Clínic de València, València, Spain.
Joan Gil-CarbonellHospital General Universitari d'Alacant, Alacant, Spain.
José TodolíHospital Universitari i Politècnic 'La Fé', València, Spain.
Jacobo MartínezFundació per al Foment de la Investigació Sanitària i Biomèdica de la Comunitat Valenciana, València, Spain.
Silvia RojoMucosal Immunology Laboratory, Institute of Biomedicine and Molecular Genetics (IBGM), University of Valladolid-CSIC, Valladolid, Spain.
Aida Fiz-LópezMucosal Immunology Laboratory, Institute of Biomedicine and Molecular Genetics (IBGM), University of Valladolid-CSIC, Valladolid, Spain.
Elisa ArribasMucosal Immunology Laboratory, Institute of Biomedicine and Molecular Genetics (IBGM), University of Valladolid-CSIC, Valladolid, Spain.
Paloma Cal-SabaterMucosal Immunology Laboratory, Institute of Biomedicine and Molecular Genetics (IBGM), University of Valladolid-CSIC, Valladolid, Spain.
David BernadoMucosal Immunology Laboratory, Institute of Biomedicine and Molecular Genetics (IBGM), University of Valladolid-CSIC, Valladolid, Spain.
Marina VogelNext Generation Sequencing Core Facility, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Stefan WiemannDivision of Molecular Genome Analysis. German Cancer Research Center (DKFZ), Heidelberg, Germany.
Hassan AbolhassaniDivision of Immunology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet, Solna, Sweden.
Qiang Pan-HammarströmDivision of Immunology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet, Solna, Sweden.
Aurora PujolNeurometabolic Diseases Laboratory, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.
COVID Human Genetic Effort
Helen C SuLaboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.
Danyel LeeSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Shen-Ying ZhangSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Jean-Laurent CasanovaSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Israel Fernández-CadenasStroke Pharmacogenomics and Genetics, Institut de Recerca Sant Pau (IR SANT PAU), Barcelona, Spain.
Jordi Pérez-TurInstitute of Biomedicine of Valencia (IBV-CSIC), València, Spain.
Anna M PlanasDepartment of Neuroscience and Experimental Therapeutics, Institute for Biomedical Research of Barcelona (IIBB-CSIC), Barcelona, Spain.

Funding

Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational SuccessUL1TR001866 · NCATS · ROCKEFELLER UNIVERSITY · PI COLLER, BARRY, KRUEGER, JAMES G · 2016 to 2025
$40.6M
ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale ModelingR01GM129325 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2018 to 2025
$5.2M
Single gene inborn errors of immunity underlying SARS-CoV-2-related multisystem inflammatory syndrome in children: a new approach to tackle a seemingly old puzzleR21AI160576 · NIAID · ROCKEFELLER UNIVERSITY · PI ZHANG, SHEN-YING · 2022 to 2023
$466k
NCATS NIH HHS UL1 TR001866NIAID NIH HHS R21 AI160576NIGMS NIH HHS R01 GM129325
6 · The paper itself

Abstract

Recessive deficiency in 2',5'-oligoadenylate synthetase (OAS) or RNase L can cause systemic inflammation in children with SARS-CoV-2 infection, but its role in adult respiratory disease is unclear. We analyzed rare

Indexed as

geneticsimmunology

Identifiers

PMID41438061
PMCPMC12719101

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.