Evidence map›Paper›PMID 41437992›Full record

ArticleFrontiers in cardiovascular medicine2025

Elevated plasma cancer antigen-125 level is associated with increased risk of new-onset atrial fibrillation after acute myocardial infarction.

Yuan Fu, Kun Zuo, Mulei Chen, Li Xu, Lin Zhao

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yuan FuHeart Center, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Kun ZuoHeart Center, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Mulei ChenHeart Center, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Li XuHeart Center, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Lin ZhaoHeart Center, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: New-onset atrial fibrillation (NOAF) is the most commonly encountered arrhythmia during the course of acute myocardial infarction (AMI) and is independently associated with a worse prognosis. Aims: We aimed to validate the discriminatory performance of cancer antigen-125 (CA-125) in predicting post-AMI NOAF in the Chinese population. Methods: A total of 488 consecutive patients with AMI from 1 January 2020 to 1 January 2022 without a previous history of AF were enrolled in this study. Risk factors for post-AMI NOAF were determined using univariable and multivariable logistic regression analyses. Receiver operating characteristic (ROC) curve analyses were used to evaluate the discrimination performance of different parameters and score models. Area under the curve (AUCs) were compared using Results: In total, 48 (9.84%) patients developed post-AMI NOAF during hospitalization. The NOAF group was older and had a higher Killip class, B-type natriuretic peptide level, CA-125 level, left atrial diameter, left ventricular end-systolic diameter, CHA Conclusion: An elevated plasma CA-125 level was independently associated with NOAF after AMI, with high discriminatory performance.

Indexed as

acute myocardial infarctioncancer antigen-125CHA2DS2-VASc scorenew-onset atrial fibrillationrisk score model

Identifiers

PMID41437992
PMCPMC12719410

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