Evidence map›Paper›PMID 41437967›Full record

ArticleNeurophotonics2025

Rapid axially scanned and de-scanned line-scan confocal microscopy with a tunable acoustic gradient index of refraction lens for high-speed volumetric

Khuong Duy Mac, Suhyeon Kim, Tien Nhat Nguyen, Christine Hwang, Minsung Kim, Rui Liu, Yan Liu, Joon Heon Kim, Young Ro Kim, Euiheon Chung and 1 more

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Article in Neurophotonics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Khuong Duy MacGwangju Institute of Science and Technology, Department of Biomedical Science and Engineering, Gwangju, Republic of Korea.ORCID https://orcid.org/0000-0001-5353-5103
Suhyeon KimGwangju Institute of Science and Technology, Department of Biomedical Science and Engineering, Gwangju, Republic of Korea.ORCID https://orcid.org/0009-0000-7409-8862
Tien Nhat NguyenGwangju Institute of Science and Technology, Department of Biomedical Science and Engineering, Gwangju, Republic of Korea.
Christine HwangGwangju Institute of Science and Technology, Department of Biomedical Science and Engineering, Gwangju, Republic of Korea.
Minsung KimGwangju Institute of Science and Technology, Department of Biomedical Science and Engineering, Gwangju, Republic of Korea.
Rui LiuUniversity of California at San Diego, Department of Physics, La Jolla, California, United States.
Yan LiuIndiana University, School of Optometry, Bloomington, Indiana, United States.
Joon Heon KimGwangju Institute of Science and Technology, Advanced Photonics Research Institute, Gwangju, Republic of Korea.
Young Ro KimMassachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, United States.
Euiheon ChungGwangju Institute of Science and Technology, Department of Biomedical Science and Engineering, Gwangju, Republic of Korea.ORCID https://orcid.org/0000-0002-3326-6927
Hyuk-Sang KwonGwangju Institute of Science and Technology, Department of Biomedical Science and Engineering, Gwangju, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: Rapid acquisition of high-resolution volumetric images has been critical to effectively monitor dynamic biological processes Aim: To address these challenges in volumetric imaging performances, we aimed to develop a high-speed volumetric imaging system capable of resolving fast biological dynamics with minimal compromise in spatial resolution or imaging depth. Approach: We devised a rapid axially scanned and de-scanned (RASAD) scheme by integrating a TAG lens (tunable acoustic gradient index of refraction lens) into a line-scan confocal microscope. The TAG lens enabled axial (depth) scanning frequency at 70 kHz, allowing 3D projection imaging at rates up to 200 Hz with a detection depth of Results: We validated its performance through Conclusions: The RASAD system enables high-speed, high-resolution 3D imaging of dynamic biological processes, providing a valuable tool for advancing studies of neurophysiological mechanisms and biomedical applications.

Indexed as

axially scanned and de-scannedcerebral blood flow imagingline-scan confocal microscopytunable acoustic gradient index of refraction lensvolumetric in vivo imaging

Identifiers

PMID41437967
PMCPMC12721343

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.