Evidence map›Paper›PMID 41437343›Full record

ArticleBMC public health2025

HPV vaccination hesitancy and acceptance among parents in Saxony-Anhalt, Germany: the role of gender, awareness and fear.

Paolo Gennari, Daniel Schlund, József Mészáros, Atanas Ignatov

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Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Paolo GennariDepartment of Gynecology and Obstetrics, Otto-von-Guericke University, Gerhard-Hauptmann-Str. 35, 39108, Magdeburg, Germany. paolo.gennari@med.ovgu.de.
Daniel SchlundDepartment of Gynecology and Obstetrics, Otto-von-Guericke University, Gerhard-Hauptmann-Str. 35, 39108, Magdeburg, Germany.
József MészárosDepartment of Gynecology and Obstetrics, Otto-von-Guericke University, Gerhard-Hauptmann-Str. 35, 39108, Magdeburg, Germany.
Atanas IgnatovDepartment of Gynecology and Obstetrics, Otto-von-Guericke University, Gerhard-Hauptmann-Str. 35, 39108, Magdeburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite national recommendations in Germany for universal HPV vaccination, uptake remains suboptimal—particularly among boys. Parental awareness, gender dynamics, and hesitancy play key roles in vaccination decisions.

methodsA cross-sectional survey was conducted among 406 parents of children aged 9–14 years in Magdeburg, Saxony-Anhalt. An anonymized online questionnaire assessed HPV-associated awareness, attitudes, willingness to vaccinate, and conditions under which hesitant parents might reconsider. Statistical analyses included chi-square tests and logistic regression. Parent–child gender dyads were examined to explore interaction effects. Vaccine hesitancy was conceptualized along a continuum from acceptance to refusal, although for analysis we contrasted parents willing to vaccinate with those refusing vaccination.

resultsMothers were significantly more aware of HPV than fathers (86.8% vs. 68.0%; p < 0.001) and more willing to vaccinate their children (90.4% vs. 74.8%; p < 0.001). Parents of daughters expressed greater fear of HPV-associated disease than parents of sons (67.5% vs. 37.4%; p < 0.001), although willingness to vaccinate did not differ by child gender. Dyadic analysis highlighted gender-specific patterns, with father–daughter pairs reporting high perceived disease risk yet comparatively lower willingness to vaccinate. Father–son pairs showed the lowest awareness and engagement overall. Logistic regression identified three determinants of willingness to vaccinate: prior awareness of HPV (OR = 3.77; p = 0.006), fear of disease (OR = 3.69; p = 0.006), and higher education (OR = 1.60; p = 0.032). Among parents who refused HPV vaccination, 80% reported that their decision would not change under any of the proposed conditions.

conclusionsGender disparities in HPV vaccine awareness and acceptance persist. Emphasizing the role of male vaccination in reducing transmission and protecting both sexes could improve uptake. Targeted strategies should strengthen engagement of all parents, with particular efforts to involve fathers and correct gendered misperceptions.

Indexed as

Health Knowledge, Attitudes, PracticePapillomavirus InfectionsPapillomavirus VaccinesParentsPatient Acceptance of Health CareVaccination HesitancyAdolescentAdultChildCross-Sectional StudiesFearFemaleGermanyHuman Papillomavirus VirusesHumansMalePapillomavirus VaccinesHPV awarenessHPV vaccinationParental attitudesVaccine hesitancy

Identifiers

PMID41437343
PMCPMC12838413

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.