Evidence map›Paper›PMID 4143721›Full record

ArticleLancet (London, England)1967

Acute respiratory distress in adults.

D G Ashbaugh, D B Bigelow, T L Petty, B E Levine

3 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in Lancet (London, England), 1967. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 870 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
870citing papers in PubMed, 3 pooled it
21.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02342756 naunknown statusnot on this mapstarted 2015, after this paper: background citation

Esophageal Pressure-Guided Optimal PEEP/mPaw in CMV and HFOV: The EPOCH Study

TypeinterventionalSponsorUniversity of TorontoRan2015 to 2017Enrolled20ConditionsRespiratory Distress Syndrome, Adult, Ventilator-Induced Lung InjuryArmsTargeting transpulmonary pressure to avoid VILI
NCT02457741 completednot on this mapstarted 2015, after this paper: background citation

A Simple Approach to Estimate Alveolar Recruitability in Patients With Acute Respiratory Distress Syndrome: a Validation Study

TypeobservationalSponsorUnity Health TorontoRan2015 to 2017Enrolled45ConditionsAcute Respiratory Distress Syndrome
NCT03202641 naterminatednot on this mapstarted 2019, after this paper: background citation

Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients: an Open Lung is a Better Heart

TypeinterventionalSponsorMassachusetts General HospitalRan2019 to 2020Enrolled2ConditionsARDS, Human, Lung Injury, Acute, Respiratory Distress Syndrome, Mechanical Ventilation ComplicationArmsPEEP ARDSnet, PEEP LRM
3 · Its place in the literature

Who cites it

870 citing papers in PubMed, 3 syntheses or guidelines pooled it, 4,224 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Successful management of long-term venovenous ECMO for severe PARDS in a child with acute lymphoblastic leukemia.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2026
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  16. Observational
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  19. ARDS and corticosteroids: beyond COVID-19.Pneumonia (Nathan Qld.) · 2026
    Review
  20. Article

810 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

D G Ashbaugh
D B Bigelow
T L Petty
B E Levine
University of Colorado Boulder · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Respiratory Distress SyndromeAcute DiseaseAdrenal Cortex HormonesAdultAnti-Bacterial AgentsBlood Gas AnalysisChildFemaleHumansLungMaleMiddle AgedPositive-Pressure RespirationRadiographyAdrenal Cortex HormonesAnti-Bacterial Agents

Identifiers

PMID4143721
OpenAlexW2037459166

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.