Evidence map›Paper›PMID 41437117›Full record

ArticleCardio-oncology (London, England)2025

Cardiogenic shock in cancer: differences in use of temporary mechanical circulatory support, invasive hemodynamic assessment and patient outcomes.

Sara Diaz Saravia, Vincent Torelli, Maninderjit Ghotra, Samuel Tan, Paulus Adinugraha, Marko Novakovic, Katharine Idrissi, Basera Sabharwal, Sean P Pinney, Gagan Sahni and 1 more

Abstract read
In one paragraph

Article in Cardio-oncology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sara Diaz SaraviaDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10025, USA.ORCID http://orcid.org/0009-0008-7462-8470
Vincent TorelliDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10025, USA.
Maninderjit GhotraDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10025, USA.
Samuel TanDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10025, USA.
Paulus AdinugrahaMount Sinai Fuster Heart Hospital, 1190 Fifth Avenue, Guggenheim Pavilion 1 West, Box 1030, New York, NY, 10029, USA.
Marko NovakovicMount Sinai Fuster Heart Hospital, 1190 Fifth Avenue, Guggenheim Pavilion 1 West, Box 1030, New York, NY, 10029, USA.
Katharine IdrissiMount Sinai Fuster Heart Hospital, 1190 Fifth Avenue, Guggenheim Pavilion 1 West, Box 1030, New York, NY, 10029, USA.
Basera SabharwalMount Sinai Fuster Heart Hospital, 1190 Fifth Avenue, Guggenheim Pavilion 1 West, Box 1030, New York, NY, 10029, USA.
Sean P PinneyMount Sinai Fuster Heart Hospital, 1190 Fifth Avenue, Guggenheim Pavilion 1 West, Box 1030, New York, NY, 10029, USA.
Gagan SahniMount Sinai Fuster Heart Hospital, 1190 Fifth Avenue, Guggenheim Pavilion 1 West, Box 1030, New York, NY, 10029, USA.
Matthew I TomeyMount Sinai Fuster Heart Hospital, 1190 Fifth Avenue, Guggenheim Pavilion 1 West, Box 1030, New York, NY, 10029, USA. matthew.tomey@mountsinai.org.ORCID http://orcid.org/0000-0001-5626-0467

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer is a growing comorbidity in patients with cardiovascular disease, but implications of cancer for treatment and outcomes of cardiogenic shock (CS) are not well described.

objectivesThis study aimed to identify associations of a cancer diagnosis with use of temporary mechanical circulatory support (tMCS) and survival in young adults hospitalized with CS.

methodsWe identified young adults (age 18–49) with CS in a large, nationwide sample of hospitalizations (years 2016–2020), and stratified cases according to history of cancer. Variables of interest included clinical and hospital characteristics, use of tMCS, and survival. Multivariable logistic regression was performed to evaluate independent associations of cancer with care and outcomes.

resultsOut of 99,335 young adults with CS, 2,705 (2.7%) had cancer. Patients with cancer had a lower burden of cardiovascular risk factors and cardiovascular disease at baseline. STEMI accounted for 13% of CS in patients without cancer compared to 4% in those with cancer. Multivariate analysis adjusted for STEMI, hypertension, diabetes, hyperlipidemia, and other cardiovascular risk factors showed that patients with cancer were less likely to receive tMCS (OR = 0.54, 95% CI 0.40–0.72, p < 0.001) and less likely to undergo pulmonary artery catheterization. They were also more likely to receive palliative care referrals, and more likely to die in the hospital (OR = 1.49, 95% CI 1.23–1.80, p < 0.001).

conclusionsAmong young adults hospitalized with CS in the United States in recent years, patients with cancer were less likely to receive tMCS and more likely to die in the hospital despite less pre-existing cardiovascular disease and fewer comorbidities.

Indexed as

CancerCardiogenic shockPulmonary artery catheterTemporary mechanical circulatory supportYoung adult

Identifiers

PMID41437117
PMCPMC12838448

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.