Evidence map›Paper›PMID 41437004›Full record

ArticleBMC public health2025

Age-dependent association between obstructive sleep apnea and self-reported history of fractures: a community-based study.

Junzhi Chen, Guangliang Shan, Yaoda Hu, Huijing He, Tong Feng, Ruohan Zhou, Ping Yuan, Miaochan Lao, Qiong Ou

Erratum issuedAbstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Junzhi ChenDepartment of Respiratory and Critical Care Medicine, Sleep Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, 106 Zhongshan Second Road, Yuexiu District, Guangzhou, 510080, China.
Guangliang ShanDepartment of Epidemiology and Statistics, Institute of Basic Medical Sciences, School of Basic Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Yaoda HuDepartment of Epidemiology and Statistics, Institute of Basic Medical Sciences, School of Basic Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Huijing HeDepartment of Epidemiology and Statistics, Institute of Basic Medical Sciences, School of Basic Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Tong FengDepartment of Respiratory and Critical Care Medicine, Sleep Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, 106 Zhongshan Second Road, Yuexiu District, Guangzhou, 510080, China.
Ruohan ZhouDepartment of Respiratory and Critical Care Medicine, Sleep Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, 106 Zhongshan Second Road, Yuexiu District, Guangzhou, 510080, China.
Ping YuanDepartment of Respiratory and Critical Care Medicine, Sleep Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, 106 Zhongshan Second Road, Yuexiu District, Guangzhou, 510080, China.
Miaochan LaoDepartment of Respiratory and Critical Care Medicine, Sleep Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, 106 Zhongshan Second Road, Yuexiu District, Guangzhou, 510080, China.
Qiong OuDepartment of Respiratory and Critical Care Medicine, Sleep Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, 106 Zhongshan Second Road, Yuexiu District, Guangzhou, 510080, China. ouqiong2776@hotmail.com.

Funding

Guangdong Provincial Science and Technology Planning Project 2023B110009Ministry of Science and Technology of the People's Republic of China 2022FY100803National Natural Science Foundation of China 82170098
6 · The paper itself

Abstract

backgroundThe relationship between obstructive sleep apnea (OSA) and self-reported history of fractures among various age groups in the general population is unclear.

methodsParticipants were recruited using a multistage probability sampling method between 2021 and 2023 in Guangdong Province, China. Sleep study was performed with a wearable type-IV monitor. OSA was defined using the oxygen desaturation index (ODI) of ≥ 5 events/h. Fracture history was self-reported according to physician diagnoses. Poor sleep quality was defined as a Pittsburgh Sleep Quality Index score > 5.

resultsA total of 5,519 participants were analyzed. The mean age of participants was 52.7 years. The prevalence rates of OSA and self-reported history of fractures were 44.5% and 13%, respectively. Participants were categorized into groups based on age tertiles. In T3 group (ages 59–91), OSA was significantly associated only with self-reported previous non-traumatic fractures (OR = 3.68, 95%CI:1.79–7.57). Similar results were observed in the T2 group (ages 48–58). OSA was not associated with self-reported history of fractures in the T1 group (ages 18–47). Furthermore, participants with both OSA and poor sleep quality had a higher odds of self-reported previous traumatic fractures compared to those with OSA alone in the T3 group (OR = 1.64, 95% CI:1.02–2.65). Interactions between OSA and age, as well as between OSA and alcohol consumption, regarding self-reported history of fractures were observed (p < 0.05).

conclusionsOSA was independently associated with self-reported previous non-traumatic fractures in the general population. The association was age-dependent and more meaningful in the elderly population.

Indexed as

Fractures, BoneSleep Apnea, ObstructiveAdolescentAdultAgedAged, 80 and overAge FactorsChinaFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsSelf ReportYoung AdultDrinkingFracturesObstructive sleep apneaPoor sleep quality

Identifiers

PMID41437004
PMCPMC12729138

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.