ArticleSpinal cord2026
Factors associated with long-term survival after traumatic and non-traumatic spinal cord injury: a 12-year population-based retrospective cohort study in Italy.
Article in Spinal cord, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designretrospective, population-based cohort study.
objectivesto evaluate long-term survival outcomes and factors affecting mortality in individuals with traumatic (TSCI) and non-traumatic spinal cord injury (NTSCI) in Italy.
settingPublicly funded rehabilitation units for SCI patients across Italy.
methodsA total of 1070 individuals with confirmed TSCI (56.5%) or NTSCI, predominantly male (70.5%), residing in the Piedmont region, were identified through admission to specialized SCI rehabilitation units (2008-2020) using administrative data. Survival probabilities were estimated using Kaplan-Meier curves; Mortality risk was assessed using multivariate Cox regression models, and adjusted hazard ratios (HRs) were reported for sex, comorbidity burden (combined Charlson Comorbidity Index, CCI), and injury level (paraplegia/tetraplegia). Causes of death were retrieved from national mortality records.
resultsThe overall case fatality rate was 25.1%, higher in NTSCI (32.9%) than in TSCI (19.2%). Mortality increased with age and comorbidity burden. Among individuals with TSCI and CCI ≥ 3, mortality risk was significantly higher (HR 1.81; 95% CI 1.29-2.53). Sex (HR 1.05) and injury level (HR 1.10) were not significant predictors. Leading causes of death were cancer in NTSCI and circulatory diseases in both groups.
conclusionsAge, comorbidities and injury type are the primary determinants of survival in SCI. The higher case fatality rate observed in NTSCI compared with TSCI underscores the prognostic relevance of etiology alongside frailty and multimorbidity. Our findings support early frailty screening, personalized comorbidity management, and the need for developing a dedicated national registry to inform long-term care strategies and improve outcomes in aging SCI populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.