ArticleEuropean radiology2026
Assessment of ultrasound-guided continuous genicular nerve radiofrequency for the management of persistent post-arthroplasty knee pain.
Article in European radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesTo evaluate the efficacy of continuous ultrasound-guided genicular nerve radiofrequency (GNRF) for managing persistent post-arthroplasty knee pain of unknown etiology. MATERIALS AND
methodsIn this single-center retrospective study, patients presenting with chronic knee pain following total knee arthroplasty, with no identifiable underlying cause and unresponsive to conventional treatments, underwent ultrasound-guided diagnostic nerve blocks followed by continuous GNRF targeting the supero-medial, supero-lateral, and infero-medial genicular nerves. Pain scores using a numeric rating scale (NRS) were assessed and compared at baseline, 1 month, and 6 months. The correlation between anesthetic nerve block test results and treatment efficacy was also analyzed.
resultsTwenty-three patients (mean age 69.9 ± 12.1 [SD], 9 men) were included between December 2021 and April 2024. At 1 month, the mean NRS score decreased from 8.0 ± 1.4 to 6.0 ± 3.4 [SD] (p = 0.01). Clinically significant pain reduction (≥ 2-point decrease) was observed in 47.8% of patients; 34.8% achieved a ≥ 50% reduction. At 6 months, the mean NRS score was 6.6 ± 3.0 [SD], with no statistically significant difference compared to baseline and 1-month NRS scores. No significant correlation was found between nerve block test outcomes and GNRF efficacy. No major complications were reported.
conclusionContinuous ultrasound-guided GNRF appears to be a safe and effective minimally invasive option for chronic post-arthroplasty knee pain with no known underlying etiology. KEY POINTS: Question Persistent post-arthroplasty knee pain with no identified underlying etiology is frequent and often difficult to manage with conventional therapies. Findings Ultrasound-guided continuous GNRF provides clinically significant pain relief at 1 month and up to 6 months. Clinical relevance Prognostic nerve blocks did not correlate with radiofrequency outcomes.
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