Evidence map›Paper›PMID 41436567›Full record

ArticleScientific reports2025

Sphingolipids as indicators of exposure to long-term air pollution: a targeted metabolomics approach.

Jeeyoung Kim, Eun Ju Lee, Ha Eun Song, Hyo Yeong Lee, Chin Kook Rhee, Sun-Young Kim, Hyun Ju Yoo, Woo Jin Kim

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jeeyoung KimDepartment of Internal Medicine and Environmental Health Center, School of Medicine, Kangwon National University Hospital, Kangwon National University, 1 Gangwondaehak-gil, Chuncheon, 24341, Republic of Korea.
Eun Ju LeeDepartment of Internal Medicine and Environmental Health Center, School of Medicine, Kangwon National University Hospital, Kangwon National University, 1 Gangwondaehak-gil, Chuncheon, 24341, Republic of Korea.
Ha Eun SongDepartment of Convergence Medicine, Asan Medical Center, Asan Institute for Life Sciences, University of Ulsan College of Medicine, Seoul, 05505, Republic of Korea.
Hyo Yeong LeeDepartment of Convergence Medicine, Asan Medical Center, Asan Institute for Life Sciences, University of Ulsan College of Medicine, Seoul, 05505, Republic of Korea.
Chin Kook RheeDepartment of Internal Medicine, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, 06591, Republic of Korea.
Sun-Young KimDepartment of Cancer Control and Population Health, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, 10408, Republic of Korea.
Hyun Ju YooDepartment of Convergence Medicine, Asan Medical Center, Asan Institute for Life Sciences, University of Ulsan College of Medicine, Seoul, 05505, Republic of Korea.
Woo Jin KimDepartment of Internal Medicine and Environmental Health Center, School of Medicine, Kangwon National University Hospital, Kangwon National University, 1 Gangwondaehak-gil, Chuncheon, 24341, Republic of Korea. pulmo2@kangwon.ac.kr.

Funding

Korea Environmental Industry and Technology Institute RS-2021-KE001380Ministry of Education RS-2025-25434262
6 · The paper itself

Abstract

Metabolomic changes related to air pollution have been previously reported, including sphingolipid metabolism; however, evidence from long-term exposures assessed with long-term exposure using targeted metabolomics remains limited. We profiled plasma sphingolipids and amino acids in 188 individuals from the chronic obstructive pulmonary disease (COPD) in Dusty Areas cohort. Annual average concentrations of particulate matter ≤ 10 μm (PM

Indexed as

Air PollutionEnvironmental ExposureMetabolomicsPulmonary Disease, Chronic ObstructiveSphingolipidsAgedAir PollutantsAmino AcidsBiomarkersFemaleHumansMaleMiddle AgedNitrogen DioxideParticulate MatterRepublic of KoreaAir PollutantsAmino AcidsBiomarkersNitrogen DioxideParticulate MatterSphingolipidsChronic obstructive pulmonary diseaseLong-term exposureMetabolomicsNitrogen dioxide (NO2)Particulate matter 10 (PM10)Sphingolipid

Identifiers

PMID41436567
PMCPMC12835267

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.