Evidence map›Paper›PMID 41436324›Full record

ArticleJournal of optometry

Transient ocular effects of red light exposure in young adults.

Jacinth J Priscilla, Lisa A Ostrin

Abstract read
In one paragraph

Article in Journal of optometry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jacinth J PriscillaUniversity of Houston College of Optometry, 4401 MLK Blvd, Houston, TX 77204, USA.
Lisa A OstrinUniversity of Houston College of Optometry, 4401 MLK Blvd, Houston, TX 77204, USA. Electronic address: Lostrin@central.uh.edu.

Funding

Light, near work, and ocular remodeling and during emmetropization and myopia development in childrenR01EY030193 · NEI · UNIVERSITY OF HOUSTON · PI Lisa A Ostrin, Jason Porter · 2019 to 2026
$2.7M
NEI NIH HHS R01 EY030193
6 · The paper itself

Abstract

purposeRed laser therapy has recently gained attention as a potential myopia treatment in children. However, concerns regarding the safety of directing red laser at the fovea have raised caution. As a result, there is growing interest in identifying alternative, safer methods of red light administration for myopia control. This study investigated whether short-term exposure to red LED light induces ocular vascular changes similar to those previously reported with red laser exposure.

methodsTwenty healthy adults (28 ± 5 years) participated in four experimental sessions each: (1) morning red LED exposure, (2) evening red LED exposure (both 5 minutes), (3) morning control, and (4) evening control. Red light (λ = 626 nm, irradiance = 0.11 mW/cm²) was delivered to the right eye using a Ganzfeld dome. Biometry, optical coherence tomography (OCT), and OCT angiography (OCTA) were performed at baseline and at 5, 30, and 60 minutes post-exposure. Changes were analyzed using two-way repeated measures ANOVAs.

resultsThere were no significant differences in axial length, choroidal thickness, or perfusion density of the superficial or deep vascular complexes between red light exposure and control conditions at 5, 30, or 60 minutes in the morning or evening (P > 0.05 for all).

conclusionFindings show that short-term exposure to red LED light does not induce significant transient changes in ocular vascular structures. While some studies have related short term choroidal thickening or increased blood flow to longer term myopia control efficacy, it cannot be concluded from the current study whether red LEDs would be effective.

Indexed as

ChoroidMyopiaRed LightAdultAxial Length, EyeBiometryFemaleHealthy VolunteersHumansMaleTomography, Optical CoherenceYoung AdultChoroidal thicknessMyopiaRed light therapyRetinal imaging

Identifiers

PMID41436324
PMCPMC13343363

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.