Evidence map›Paper›PMID 41436181›Full record

ArticleArchives of disease in childhood2026

Long-term association between the COVID-19 pandemic and language development in children aged 18 months: effect modification by sex, childcare location and family size.

Rumi Matsuo, Naomi Matsumoto, Kazue Nakamura, Toshiharu Mitsuhashi, Takashi Yorifuji

Abstract read
In one paragraph

Article in Archives of disease in childhood, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rumi MatsuoDepartment of Epidemiology, Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama, Japan p8iw4dau@okayama-u.ac.jp.ORCID 0000-0001-9162-1395
Naomi MatsumotoDepartment of Epidemiology, Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.ORCID 0000-0002-9980-6092
Kazue NakamuraDepartment of Epidemiology, Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama, Japan.ORCID 0000-0003-3180-5744
Toshiharu MitsuhashiCenter for Innovative Clinical Medicine, Okayama University Hospital, Okayama, Japan.ORCID 0000-0001-9940-0570
Takashi YorifujiDepartment of Epidemiology, Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.ORCID 0000-0003-2543-5441

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe evaluated the long-term association between the COVID-19 pandemic and the language development of children aged 18 months by comparing prepandemic and pandemic periods in Japan. STUDY

designThis repeated cross-sectional study included 39 840 children attending 18-month health check-ups conducted by the Okayama City Public Health Center (January 2017-March 2024). We compared language development indicators before (January 2017-March 2020) and during (April 2020-March 2024) the pandemic, with the latter divided into early (April 2020-March 2022) and late (April 2022-March 2024) periods. The primary outcome was the proportion of children requiring language development follow-up (children who did not meet any one of the three questions on language development). The secondary outcome was the proportion of children who could not say ≥3 meaningful words (one of the three questions). Risk ratios (RRs) and 95% CIs were estimated adjusting for confounders, with subgroup analyses by sex, childcare location (home, nursery school) and family size (≤3, ≥4).

resultsCompared with the prepandemic period, increased RRs were observed during the pandemic: 1.19 (95% CI 1.15 to 1.22) for the primary outcome and 1.16 (95% CI 1.11 to 1.22) for the secondary outcome. RRs were higher in the late than in the early period. Adverse associations were more pronounced in girls than boys, and in children cared for at home.

conclusionThe long-term association between the pandemic and language development at 18 months suggests the need for more comprehensive support for high-risk families.

Indexed as

COVID-19Family CharacteristicsLanguage DevelopmentChild CareCross-Sectional StudiesFemaleHumansInfantJapanMalePandemicsSARS-CoV-2Sex Factorschild developmentchild healthCOVID-19paediatrics

Identifiers

PMID41436181
PMCPMC13151506

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.